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Pharmacophore-Based Discovery of Substrates of a Novel Drug/Proton-Antiporter in the Human Brain Endothelial hCMEC/D3 Cell Line

A drug/proton-antiporter, whose the molecular structure is still unknown, was previously evidenced at the blood-brain barrier (BBB) by functional experiments. The computational method could help in the identification of substrates of this solute carrier (SLC) transporter. Two pharmacophore models fo...

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Detalles Bibliográficos
Autores principales:	Smirnova, Maria, Goracci, Laura, Cruciani, Gabriele, Federici, Laetitia, Declèves, Xavier, Chapy, Hélène, Cisternino, Salvatore
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8875908/ https://www.ncbi.nlm.nih.gov/pubmed/35213988 http://dx.doi.org/10.3390/pharmaceutics14020255

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