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miRNome Profiling and Functional Analysis Reveal Involvement of hsa-miR-1246 in Colon Adenoma-Carcinoma Transition by Targeting AXIN2 and CFTR

Regulatory changes occurring early in colorectal cancer development remain poorly investigated. Since the majority of cases develop from polyps in the adenoma-carcinoma transition, a search of early molecular features, such as aberrations in miRNA expression occurring prior to cancer development, wo...

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Detalles Bibliográficos
Autores principales: Lukosevicius, Rokas, Juzenas, Simonas, Salteniene, Violeta, Kulokiene, Ugne, Arstikyte, Justina, Hemmrich-Stanisak, Georg, Franke, Andre, Link, Alexander, Ruzgys, Paulius, Satkauskas, Saulius, Pauzas, Henrikas, Latkauskas, Tadas, Kiudelis, Gediminas, Balaguer, Francesc, Kupcinskas, Juozas, Skieceviciene, Jurgita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8876010/
https://www.ncbi.nlm.nih.gov/pubmed/35216222
http://dx.doi.org/10.3390/ijms23042107

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