Cell Cycle Stage and DNA Repair Pathway Influence CRISPR/Cas9 Gene Editing Efficiency in Porcine Embryos

CRISPR/Cas9 technology is a powerful tool used for genome manipulation in different cell types and species. However, as with all new technologies, it still requires improvements. Different factors can affect CRISPR/Cas efficiency in zygotes, which influence the total cost and complexity for creating...

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Detalles Bibliográficos
Autores principales: Gutierrez, Karina, Glanzner, Werner G., de Macedo, Mariana P., Rissi, Vitor B., Dicks, Naomi, Bohrer, Rodrigo C., Baldassarre, Hernan, Agellon, Luis B., Bordignon, Vilceu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8876063/
https://www.ncbi.nlm.nih.gov/pubmed/35207459
http://dx.doi.org/10.3390/life12020171

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