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Focused Ultrasound-Induced Blood–Brain Barrier Opening Enhanced α-Synuclein Expression in Mice for Modeling Parkinson’s Disease

Parkinson’s disease (PD) is characterized by α-synuclein (αSNCA) aggregation in dopaminergic neurons. Gradual accumulation of αSNCA aggregates in substantia nigra (SN) diminishes the normal functioning of soluble αSNCA, leading to a loss of dopamine (DA) neurons. In this study, we developed focused...

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Detalles Bibliográficos
Autores principales:	Lin, Chung-Yin, Huang, Ching-Yun, Chen, Chiung-Mei, Liu, Hao-Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8876143/ https://www.ncbi.nlm.nih.gov/pubmed/35214176 http://dx.doi.org/10.3390/pharmaceutics14020444

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