Cargando…
Production of Fungal Nanochitosan Using High-Pressure Water Jet System for Biomedical Applications
In this present work, fungal nanochitosans, with very interesting particle size distribution of 22 µm, were efficiently generated in high-yield production using a high-pressure water jet system (Star Burst System, Sugino, Japan) after 10 passes of mechanical treatment under high pressure. The specif...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8876192/ https://www.ncbi.nlm.nih.gov/pubmed/35207915 http://dx.doi.org/10.3390/ma15041375 |
_version_ | 1784658107859730432 |
---|---|
author | Ogura, Kota Brasselet, Clément Cabrera-Barjas, Gustavo Hamidi, Masoud Shavandi, Amin Dols-Lafargue, Marguerite Sawamura, Naoki Delattre, Cédric |
author_facet | Ogura, Kota Brasselet, Clément Cabrera-Barjas, Gustavo Hamidi, Masoud Shavandi, Amin Dols-Lafargue, Marguerite Sawamura, Naoki Delattre, Cédric |
author_sort | Ogura, Kota |
collection | PubMed |
description | In this present work, fungal nanochitosans, with very interesting particle size distribution of 22 µm, were efficiently generated in high-yield production using a high-pressure water jet system (Star Burst System, Sugino, Japan) after 10 passes of mechanical treatment under high pressure. The specific characterization of fungal chitosan nanofibers suspensions in water revealed a high viscosity of 1450 mPa.s and an estimated transparency of 43.5% after 10 passes of fibrillation mechanical treatment. The mechanical characterization of fungal nanochitosan (NC) film are very interesting for medical applications with a Young’s modulus (E), a tensile strength (TS), and elongation at break (e%) estimated at 2950 MPa, 50.5 MPa, and 5.5%, respectively. Furthermore, we exhibited that the fungal nanochitosan (NC) film presented very good long-term antioxidant effect (reached 82.4% after 96 h of contact with DPPH radical solution) and very interesting antimicrobial activity when the nanochitosan (NC) fibers are mainly activated as NC-NH(3)(+) form at the surface of the film with 45% reduction and 75% reduction observed for S. aureus (Gram-positive) and E. coli (Gram-negative), respectively, after 6 h of treatment. These promising antimicrobial and antioxidant activities indicated the high potential of valorization toward biomedical applications. |
format | Online Article Text |
id | pubmed-8876192 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-88761922022-02-26 Production of Fungal Nanochitosan Using High-Pressure Water Jet System for Biomedical Applications Ogura, Kota Brasselet, Clément Cabrera-Barjas, Gustavo Hamidi, Masoud Shavandi, Amin Dols-Lafargue, Marguerite Sawamura, Naoki Delattre, Cédric Materials (Basel) Article In this present work, fungal nanochitosans, with very interesting particle size distribution of 22 µm, were efficiently generated in high-yield production using a high-pressure water jet system (Star Burst System, Sugino, Japan) after 10 passes of mechanical treatment under high pressure. The specific characterization of fungal chitosan nanofibers suspensions in water revealed a high viscosity of 1450 mPa.s and an estimated transparency of 43.5% after 10 passes of fibrillation mechanical treatment. The mechanical characterization of fungal nanochitosan (NC) film are very interesting for medical applications with a Young’s modulus (E), a tensile strength (TS), and elongation at break (e%) estimated at 2950 MPa, 50.5 MPa, and 5.5%, respectively. Furthermore, we exhibited that the fungal nanochitosan (NC) film presented very good long-term antioxidant effect (reached 82.4% after 96 h of contact with DPPH radical solution) and very interesting antimicrobial activity when the nanochitosan (NC) fibers are mainly activated as NC-NH(3)(+) form at the surface of the film with 45% reduction and 75% reduction observed for S. aureus (Gram-positive) and E. coli (Gram-negative), respectively, after 6 h of treatment. These promising antimicrobial and antioxidant activities indicated the high potential of valorization toward biomedical applications. MDPI 2022-02-12 /pmc/articles/PMC8876192/ /pubmed/35207915 http://dx.doi.org/10.3390/ma15041375 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Ogura, Kota Brasselet, Clément Cabrera-Barjas, Gustavo Hamidi, Masoud Shavandi, Amin Dols-Lafargue, Marguerite Sawamura, Naoki Delattre, Cédric Production of Fungal Nanochitosan Using High-Pressure Water Jet System for Biomedical Applications |
title | Production of Fungal Nanochitosan Using High-Pressure Water Jet System for Biomedical Applications |
title_full | Production of Fungal Nanochitosan Using High-Pressure Water Jet System for Biomedical Applications |
title_fullStr | Production of Fungal Nanochitosan Using High-Pressure Water Jet System for Biomedical Applications |
title_full_unstemmed | Production of Fungal Nanochitosan Using High-Pressure Water Jet System for Biomedical Applications |
title_short | Production of Fungal Nanochitosan Using High-Pressure Water Jet System for Biomedical Applications |
title_sort | production of fungal nanochitosan using high-pressure water jet system for biomedical applications |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8876192/ https://www.ncbi.nlm.nih.gov/pubmed/35207915 http://dx.doi.org/10.3390/ma15041375 |
work_keys_str_mv | AT ogurakota productionoffungalnanochitosanusinghighpressurewaterjetsystemforbiomedicalapplications AT brasseletclement productionoffungalnanochitosanusinghighpressurewaterjetsystemforbiomedicalapplications AT cabrerabarjasgustavo productionoffungalnanochitosanusinghighpressurewaterjetsystemforbiomedicalapplications AT hamidimasoud productionoffungalnanochitosanusinghighpressurewaterjetsystemforbiomedicalapplications AT shavandiamin productionoffungalnanochitosanusinghighpressurewaterjetsystemforbiomedicalapplications AT dolslafarguemarguerite productionoffungalnanochitosanusinghighpressurewaterjetsystemforbiomedicalapplications AT sawamuranaoki productionoffungalnanochitosanusinghighpressurewaterjetsystemforbiomedicalapplications AT delattrecedric productionoffungalnanochitosanusinghighpressurewaterjetsystemforbiomedicalapplications |