Cargando…

Molecular Pathological Diagnosis of Thyroid Tumors Using Spatially Resolved Metabolomics

The pathological diagnosis of benign and malignant follicular thyroid tumors remains a major challenge using the current histopathological technique. To improve diagnosis accuracy, spatially resolved metabolomics analysis based on air flow-assisted desorption electrospray ionization mass spectrometr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Huang, Luojiao, Mao, Xinxin, Sun, Chenglong, Li, Tiegang, Song, Xiaowei, Li, Jiangshuo, Gao, Shanshan, Zhang, Ruiping, Chen, Jie, He, Jiuming, Abliz, Zeper
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8876246/ https://www.ncbi.nlm.nih.gov/pubmed/35209182 http://dx.doi.org/10.3390/molecules27041390

Ejemplares similares

Identification of Diagnostic Metabolic Signatures in Thyroid Tumors Using Mass Spectrometry Imaging
por: Mao, Xinxin, et al.
Publicado: (2023)

Spatially resolved metabolomics to discover tumor-associated metabolic alterations
por: Sun, Chenglong, et al.
Publicado: (2019)

A Sensitive and Wide Coverage Ambient Mass Spectrometry Imaging Method for Functional Metabolites Based Molecular Histology
por: He, Jiuming, et al.
Publicado: (2018)

Application of imaging mass spectrometry for the molecular diagnosis of human breast tumors
por: Mao, Xinxin, et al.
Publicado: (2016)

Spatiotemporally resolved metabolomics and isotope tracing reveal CNS drug targets
por: Jin, Bo, et al.
Publicado: (2023)

Rapid and sensitive liquid chromatography–tandem mass spectrometric method for the quantitative determination of potentially harmful substance 5,5′-oxydimethylenebis (2-furfural) in traditional Chinese medicine injections
por: Zang, Qingce, et al.
Publicado: (2018)

Global metabolomics reveals potential urinary biomarkers of esophageal squamous cell carcinoma for diagnosis and staging
por: Xu, Jing, et al.
Publicado: (2016)

Evaluation of the tumor-targeting efficiency and intratumor heterogeneity of anticancer drugs using quantitative mass spectrometry imaging
por: Zhang, Jin, et al.
Publicado: (2020)

In situ biomarker discovery and label-free molecular histopathological diagnosis of lung cancer by ambient mass spectrometry imaging
por: Li, Tiegang, et al.
Publicado: (2015)

Accurate Classification of Non-small Cell Lung Cancer (NSCLC) Pathology and Mapping of EGFR Mutation Spatial Distribution by Ambient Mass Spectrometry Imaging
por: Zhang, Min, et al.
Publicado: (2019)

A targeted neurotransmitter quantification and nontargeted metabolic profiling method for pharmacometabolomics analysis of olanzapine by using UPLC-HRMS
por: Liu, Dan, et al.
Publicado: (2020)

Spatiotemporal pharmacometabolomics based on ambient mass spectrometry imaging to evaluate the metabolism and hepatotoxicity of amiodarone in HepG2 spheroids
por: Li, Limei, et al.
Publicado: (2023)

Spatial-resolved metabolomics reveals tissue-specific metabolic reprogramming in diabetic nephropathy by using mass spectrometry imaging
por: Wang, Zhonghua, et al.
Publicado: (2021)

Rewiring of purine metabolism in response to acidosis stress in glioma stem cells
por: Xu, Xiaoyu, et al.
Publicado: (2021)

Ratiometric Mass Spectrometry Imaging for Stain-Free Delineation of Ischemic Tissue and Spatial Profiling of Ischemia-Related Molecular Signatures
por: Wang, Zixuan, et al.
Publicado: (2021)

Promise of spatially resolved omics for tumor research
por: Zhou, Yanhe, et al.
Publicado: (2023)

Discovering metabolic vulnerability using spatially resolved metabolomics for antitumor small molecule-drug conjugates development as a precise cancer therapy strategy
por: Wang, Xiangyi, et al.
Publicado: (2023)

Mass spectrometry imaging-based metabolomics to visualize the spatially resolved reprogramming of carnitine metabolism in breast cancer
por: Sun, Chenglong, et al.
Publicado: (2020)

In situ metabolomics in nephrotoxicity of aristolochic acids based on air flow-assisted desorption electrospray ionization mass spectrometry imaging
por: Wang, Zhonghua, et al.
Publicado: (2020)

Spatially resolved multi-omics highlights cell-specific metabolic remodeling and interactions in gastric cancer
por: Sun, Chenglong, et al.
Publicado: (2023)

Spatially resolved 3D metabolomic profiling in tissues
por: Ganesh, Shambavi, et al.
Publicado: (2021)

SpatialDB: a database for spatially resolved transcriptomes
por: Fan, Zhen, et al.
Publicado: (2020)

Spatially resolved sampling for untargeted metabolomics: A new tool for salivomics
por: Ciurli, Alessio, et al.
Publicado: (2021)

Bulk and Spatially Resolved Extracellular Metabolome of Free-Living Nitrogen Fixation
por: Smercina, Darian N., et al.
Publicado: (2022)

Spatially Resolved Mass Spectrometry at the Single Cell: Recent Innovations in Proteomics and Metabolomics
por: Taylor, Michael J., et al.
Publicado: (2021)

Toward Gene-Correlated Spatially Resolved Metabolomics with Fingerprint Coherent Raman Imaging
por: Poorna, Rajas, et al.
Publicado: (2023)

Morus alba L. (Sangzhi) Alkaloids Promote Insulin Secretion, Restore Diabetic β-Cell Function by Preventing Dedifferentiation and Apoptosis
por: Lei, Lei, et al.
Publicado: (2022)

The Potential of Metabolomics in the Diagnosis of Thyroid Cancer
por: Coelho, Margarida, et al.
Publicado: (2020)

Evaluation of Formalin-Fixed and FFPE Tissues for Spatially Resolved Metabolomics and Drug Distribution Studies
por: Dannhorn, Andreas, et al.
Publicado: (2022)

Correction to “Toward Gene-Correlated Spatially Resolved Metabolomics with Fingerprint Coherent Raman Imaging”
por: Poorna, Rajas, et al.
Publicado: (2023)

Untargeted and spatial-resolved metabolomics characterize serum and tissue-specific metabolic reprogramming in acute kidney injury
por: Xu, Bei, et al.
Publicado: (2023)

Incorporation of a machine learning pathological diagnosis algorithm into the thyroid ultrasound imaging data improves the diagnosis risk of malignant thyroid nodules
por: Li, Wanying, et al.
Publicado: (2022)

Spatially resolved visualization of reprogrammed metabolism in hepatocellular carcinoma by mass spectrometry imaging
por: Ma, Bangzhen, et al.
Publicado: (2023)

A temporo-spatial pharmacometabolomics method to characterize pharmacokinetics and pharmacodynamics in the brain microregions by using ambient mass spectrometry imaging
por: Liu, Dan, et al.
Publicado: (2022)

Systematic Evaluation of HILIC Stationary Phases for Global Metabolomics of Human Plasma
por: Hosseinkhani, Farideh, et al.
Publicado: (2022)

Define and visualize pathological architectures of human tissues from spatially resolved transcriptomics using deep learning
por: Chang, Yuzhou, et al.
Publicado: (2022)

Performance evaluation of multi-junction solar cells by spatially resolved electroluminescence microscopy
por: Kong, Lijing, et al.
Publicado: (2015)

Spatially Resolved Transcriptomics Technology Facilitates Cancer Research
por: Wang, Qian, et al.
Publicado: (2023)

Spatially resolved metabolomics reveals variety-specific metabolic changes in banana pulp during postharvest senescence
por: Yin, Zhibin, et al.
Publicado: (2022)

Spatial cancer systems biology resolves heterotypic interactions and identifies disruption of spatial hierarchy as a pathological driver event
por: Filipp, Fabian V.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_lcbibic10thm1908qjbqeg4762