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Akt1 Decreases Gcn5 Protein Stability through Regulating The Ubiquitin-Proteasome Pathway in Mouse Embryonic Fibroblasts

General control non-derepressible 5 (Gcn5) is a member of histone acetyltransferase (HAT) that plays key roles during embryogenesis as well as in the development of various human cancers. Gcn5, an epigenetic regulator of Hoxc11, has been reported to be negatively regulated by Akt1 in the mouse embry...

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Detalles Bibliográficos
Autores principales: Jeong, Da Som, Kim, Yu Cheon, Oh, Ji Hoon, Kim, Myoung Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royan Institute 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8876264/
https://www.ncbi.nlm.nih.gov/pubmed/35182065
http://dx.doi.org/10.22074/cellj.2022.7961

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