SARS-CoV-2 Infects Primary Neurons from Human ACE2 Expressing Mice and Upregulates Genes Involved in the Inflammatory and Necroptotic Pathways

Transgenic mice expressing human angiotensin-converting enzyme 2 under the cytokeratin 18 promoter (K18-hACE2) have been extensively used to investigate the pathogenesis and tissue tropism of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection. Neuroinvasion and the replication of...

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Detalles Bibliográficos
Autores principales: Rothan, Hussin A., Kumari, Pratima, Stone, Shannon, Natekar, Janhavi P., Arora, Komal, Auroni, Tabassum T., Kumar, Mukesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8876293/
https://www.ncbi.nlm.nih.gov/pubmed/35215199
http://dx.doi.org/10.3390/pathogens11020257

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8876293/
https://www.ncbi.nlm.nih.gov/pubmed/35215199
http://dx.doi.org/10.3390/pathogens11020257

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