MiR-30 promotes fatty acid beta-oxidation and endothelial cell dysfunction and is a circulating biomarker of coronary microvascular dysfunction in pre-clinical models of diabetes

BACKGROUND: Type 2 diabetes (T2D) is associated with coronary microvascular dysfunction, which is thought to contribute to compromised diastolic function, ultimately culminating in heart failure with preserved ejection fraction (HFpEF). The molecular mechanisms remain incompletely understood, and no...

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Detalles Bibliográficos
Autores principales: Veitch, Shawn, Njock, Makon-Sébastien, Chandy, Mark, Siraj, M. Ahsan, Chi, Lijun, Mak, HaoQi, Yu, Kai, Rathnakumar, Kumaragurubaran, Perez-Romero, Carmina Anjelica, Chen, Zhiqi, Alibhai, Faisal J., Gustafson, Dakota, Raju, Sneha, Wu, Ruilin, Zarrin Khat, Dorrin, Wang, Yaxu, Caballero, Amalia, Meagher, Patrick, Lau, Edward, Pepic, Lejla, Cheng, Henry S., Galant, Natalie J., Howe, Kathryn L., Li, Ren-Ke, Connelly, Kim A., Husain, Mansoor, Delgado-Olguin, Paul, Fish, Jason E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8876371/
https://www.ncbi.nlm.nih.gov/pubmed/35209901
http://dx.doi.org/10.1186/s12933-022-01458-z

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