Myofibroblast YAP/TAZ activation is a key step in organ fibrogenesis

Fibrotic diseases account for nearly half of all deaths in the developed world. Despite its importance, the pathogenesis of fibrosis remains poorly understood. Recently, the two mechanosensitive transcription cofactors YAP and TAZ have emerged as important profibrotic regulators in multiple murine t...

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Detalles Bibliográficos
Autores principales: He, Xiaolin, Tolosa, Monica F., Zhang, Tianzhou, Goru, Santosh Kumar, Ulloa Severino, Luisa, Misra, Paraish S., McEvoy, Caitríona M., Caldwell, Lauren, Szeto, Stephen G., Gao, Feng, Chen, Xiaolan, Atin, Cassandra, Ki, Victoria, Vukosa, Noah, Hu, Catherine, Zhang, Johnny, Yip, Christopher, Krizova, Adriana, Wrana, Jeffrey L., Yuen, Darren A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8876427/
https://www.ncbi.nlm.nih.gov/pubmed/35191398
http://dx.doi.org/10.1172/jci.insight.146243

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