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Limited induction of SARS-CoV-2–specific T cell responses in children with multisystem inflammatory syndrome compared with COVID-19

Why multisystem inflammatory syndrome in children (MIS-C) develops after SARS-CoV-2 infection in a subset of children is unknown. We hypothesized that aberrant virus–specific T cell responses contribute to MIS-C pathogenesis. We quantified SARS-CoV-2–reactive T cells, serologic responses against maj...

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Detalles Bibliográficos
Autores principales:	Singh, Vidisha, Obregon-Perko, Veronica, Lapp, Stacey A., Horner, Anna Marie, Brooks, Alyssa, Macoy, Lisa, Hussaini, Laila, Lu, Austin, Gibson, Theda, Silvestri, Guido, Grifoni, Alba, Weiskopf, Daniela, Sette, Alessandro, Anderson, Evan J., Rostad, Christina A., Chahroudi, Ann
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Clinical Investigation 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8876428/ https://www.ncbi.nlm.nih.gov/pubmed/35044955 http://dx.doi.org/10.1172/jci.insight.155145

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