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Zinc finger protein 277 is an intestinal transit-amplifying cell marker and colon cancer oncogene
Sustained proliferative signaling and resisting cell death are hallmarks of cancer. Zinc finger protein 277 (ZNF277; murine Zfp277), a transcription factor regulating cellular senescence, is overexpressed in colon cancer, but its actions in intestinal homeostasis and neoplasia are unclear. Using hum...
Autores principales: | Xie, Guofeng, Peng, Zhongsheng, Liang, Jinqing, Larabee, Shannon M., Drachenberg, Cinthia B., Yfantis, Harris, Raufman, Jean-Pierre |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8876557/ https://www.ncbi.nlm.nih.gov/pubmed/35015732 http://dx.doi.org/10.1172/jci.insight.150894 |
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