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Human-Based Immune Responsive In Vitro Infection Models for Validation of Novel TLR4 Antagonists Identified by Computational Discovery

Infectious diseases are still a major problem worldwide. This includes microbial infections, with a constant increase in resistance to the current anti-infectives employed. Toll-like receptors (TLRs) perform a fundamental role in pathogen recognition and activation of the innate immune response. Pro...

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Detalles Bibliográficos
Autores principales:	Merk, Helena, Amran-Gealia, Tehila, Finkelmeier, Doris, Kohl, Christina, Pichota, Isabelle, Stern, Noa, Rupp, Steffen, Goldblum, Amiram, Burger-Kentischer, Anke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8876567/ https://www.ncbi.nlm.nih.gov/pubmed/35208698 http://dx.doi.org/10.3390/microorganisms10020243

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