In Vitro–In Silico Modeling of Caffeine and Diclofenac Permeation in Static and Fluidic Systems with a 16HBE Lung Cell Barrier

Static in vitro permeation experiments are commonly used to gain insights into the permeation properties of drug substances but exhibit limitations due to missing physiologic cell stimuli. Thus, fluidic systems integrating stimuli, such as physicochemical fluxes, have been developed. However, as flu...

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Detalles Bibliográficos
Autores principales: Kovar, Lukas, Wien, Lena, Selzer, Dominik, Kohl, Yvonne, Bals, Robert, Lehr, Thorsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8876625/
https://www.ncbi.nlm.nih.gov/pubmed/35215362
http://dx.doi.org/10.3390/ph15020250

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8876625/
https://www.ncbi.nlm.nih.gov/pubmed/35215362
http://dx.doi.org/10.3390/ph15020250

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