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Microangiopathy in Inflammatory Diseases—Strategies in Surgery of the Lower Extremity

Background: Patients with an inflammatory disease frequently develop chronic angiopathy of the capillaries. Due to this pathology, there is an increased rate of complications in lower extremity surgical procedures. It is not uncommon for microangiopathic wound healing disorders to cause deep infecti...

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Autores principales: Biehl, Christoph, Biehl, Lotta, Tarner, Ingo Helmut, Müller-Ladner, Ulf, Heiss, Christian, Heinrich, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8876644/
https://www.ncbi.nlm.nih.gov/pubmed/35207487
http://dx.doi.org/10.3390/life12020200
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author Biehl, Christoph
Biehl, Lotta
Tarner, Ingo Helmut
Müller-Ladner, Ulf
Heiss, Christian
Heinrich, Martin
author_facet Biehl, Christoph
Biehl, Lotta
Tarner, Ingo Helmut
Müller-Ladner, Ulf
Heiss, Christian
Heinrich, Martin
author_sort Biehl, Christoph
collection PubMed
description Background: Patients with an inflammatory disease frequently develop chronic angiopathy of the capillaries. Due to this pathology, there is an increased rate of complications in lower extremity surgical procedures. It is not uncommon for microangiopathic wound healing disorders to cause deep infections and fistulas, which lead to prolonged courses and hospitalizations. In addition, adhesions and ossifications of the contractile elements occur regularly. This sometimes results in serious limitations of the mobility of the patients. The study aims to present the results of a combination of vacuum and physical therapy. Patient and methods: A retrospective study of six patients with systemic sclerosis undergoing joint-related procedures of the lower extremity between 2015 and 2020 was performed. In addition to characterization of the patients and therapy, special attention was paid to cutaneous wound healing, affection of the fascia and displacement layers, and sclerosis of the muscle and tendon insertion. Results: The characterized structures (skin, tendon, fascia) show pathological changes at the microangiopathic level, which are associated with delayed healing and less physical capacity. Early suture removal regularly results in secondary scar dehiscence. With a stage-adapted vacuum therapy with sanitation of the deep structures and later on a dermal vacuum system, healing with simultaneous mobilization of the patients could be achieved in our patient cohort. Conclusion: In the case of necessary interventions on the lower extremity, such as trauma surgery, additional decongestive measures in the sense of regular and sustained lymphatic therapy and adapted physiotherapy are indispensable.
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spelling pubmed-88766442022-02-26 Microangiopathy in Inflammatory Diseases—Strategies in Surgery of the Lower Extremity Biehl, Christoph Biehl, Lotta Tarner, Ingo Helmut Müller-Ladner, Ulf Heiss, Christian Heinrich, Martin Life (Basel) Article Background: Patients with an inflammatory disease frequently develop chronic angiopathy of the capillaries. Due to this pathology, there is an increased rate of complications in lower extremity surgical procedures. It is not uncommon for microangiopathic wound healing disorders to cause deep infections and fistulas, which lead to prolonged courses and hospitalizations. In addition, adhesions and ossifications of the contractile elements occur regularly. This sometimes results in serious limitations of the mobility of the patients. The study aims to present the results of a combination of vacuum and physical therapy. Patient and methods: A retrospective study of six patients with systemic sclerosis undergoing joint-related procedures of the lower extremity between 2015 and 2020 was performed. In addition to characterization of the patients and therapy, special attention was paid to cutaneous wound healing, affection of the fascia and displacement layers, and sclerosis of the muscle and tendon insertion. Results: The characterized structures (skin, tendon, fascia) show pathological changes at the microangiopathic level, which are associated with delayed healing and less physical capacity. Early suture removal regularly results in secondary scar dehiscence. With a stage-adapted vacuum therapy with sanitation of the deep structures and later on a dermal vacuum system, healing with simultaneous mobilization of the patients could be achieved in our patient cohort. Conclusion: In the case of necessary interventions on the lower extremity, such as trauma surgery, additional decongestive measures in the sense of regular and sustained lymphatic therapy and adapted physiotherapy are indispensable. MDPI 2022-01-28 /pmc/articles/PMC8876644/ /pubmed/35207487 http://dx.doi.org/10.3390/life12020200 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Biehl, Christoph
Biehl, Lotta
Tarner, Ingo Helmut
Müller-Ladner, Ulf
Heiss, Christian
Heinrich, Martin
Microangiopathy in Inflammatory Diseases—Strategies in Surgery of the Lower Extremity
title Microangiopathy in Inflammatory Diseases—Strategies in Surgery of the Lower Extremity
title_full Microangiopathy in Inflammatory Diseases—Strategies in Surgery of the Lower Extremity
title_fullStr Microangiopathy in Inflammatory Diseases—Strategies in Surgery of the Lower Extremity
title_full_unstemmed Microangiopathy in Inflammatory Diseases—Strategies in Surgery of the Lower Extremity
title_short Microangiopathy in Inflammatory Diseases—Strategies in Surgery of the Lower Extremity
title_sort microangiopathy in inflammatory diseases—strategies in surgery of the lower extremity
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8876644/
https://www.ncbi.nlm.nih.gov/pubmed/35207487
http://dx.doi.org/10.3390/life12020200
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