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Disaggregation of Islet Amyloid Polypeptide Fibrils as a Potential Anti-Fibrillation Mechanism of Tetrapeptide TNGQ

Islet amyloid polypeptide (IAPP) fibrillation has been commonly associated with the exacerbation of type 2 diabetes prognosis. Consequently, inhibition of IAPP fibrillation to minimize β-cell cytotoxicity is an important approach towards β-cell preservation and type 2 diabetes management. In this st...

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Detalles Bibliográficos
Autores principales: Abioye, Raliat O., Okagu, Ogadimma D., Udenigwe, Chibuike C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8876742/
https://www.ncbi.nlm.nih.gov/pubmed/35216095
http://dx.doi.org/10.3390/ijms23041972

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