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Ribosomal DNA methylation in human and mouse oocytes increases with age

An age-dependent increase in ribosomal DNA (rDNA) methylation has been observed across a broad spectrum of somatic tissues and the male mammalian germline. Bisulfite pyrosequencing (BPS) was used to determine the methylation levels of the rDNA core promoter and the rDNA upstream control element (UCE...

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Detalles Bibliográficos
Autores principales:	Potabattula, Ramya, Trapphoff, Tom, Dittrich, Marcus, Fic, Kinga, Ptak, Grazyna E., Dieterle, Stefan, Haaf, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8876901/ https://www.ncbi.nlm.nih.gov/pubmed/35157611 http://dx.doi.org/10.18632/aging.203891

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