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Puerarin inhibits FUNDC1-mediated mitochondrial autophagy and CSE-induced apoptosis of human bronchial epithelial cells by activating the PI3K/AKT/mTOR signaling pathway

Increasing evidence suggests that the pathogenesis of chronic obstructive pulmonary disease (COPD) is associated with FUN14 domain protein 1 (FUNDC1)-mediated mitophagy. Recently, studies have reported that puerarin has protective effects against excessive oxidative damage in cells. Therefore, we hy...

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Detalles Bibliográficos
Autores principales:	Wang, Li, Jiang, Weizhou, Wang, Jing, Xie, Yuanyuan, Wang, Weisi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8876910/ https://www.ncbi.nlm.nih.gov/pubmed/35134750 http://dx.doi.org/10.18632/aging.203317

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