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PLGA-Based Composites for Various Biomedical Applications

Polymeric materials have been extensively explored in the field of nanomedicine; within them, poly lactic-co-glycolic acid (PLGA) holds a prominent position in micro- and nanotechnology due to its biocompatibility and controllable biodegradability. In this review we focus on the combination of PLGA...

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Autores principales: Rocha, Cátia Vieira, Gonçalves, Victor, da Silva, Milene Costa, Bañobre-López, Manuel, Gallo, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8876940/
https://www.ncbi.nlm.nih.gov/pubmed/35216149
http://dx.doi.org/10.3390/ijms23042034
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author Rocha, Cátia Vieira
Gonçalves, Victor
da Silva, Milene Costa
Bañobre-López, Manuel
Gallo, Juan
author_facet Rocha, Cátia Vieira
Gonçalves, Victor
da Silva, Milene Costa
Bañobre-López, Manuel
Gallo, Juan
author_sort Rocha, Cátia Vieira
collection PubMed
description Polymeric materials have been extensively explored in the field of nanomedicine; within them, poly lactic-co-glycolic acid (PLGA) holds a prominent position in micro- and nanotechnology due to its biocompatibility and controllable biodegradability. In this review we focus on the combination of PLGA with different inorganic nanomaterials in the form of nanocomposites to overcome the polymer’s limitations and extend its field of applications. We discuss their physicochemical properties and a variety of well-established synthesis methods for the preparation of different PLGA-based materials. Recent progress in the design and biomedical applications of PLGA-based materials are thoroughly discussed to provide a framework for future research.
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spelling pubmed-88769402022-02-26 PLGA-Based Composites for Various Biomedical Applications Rocha, Cátia Vieira Gonçalves, Victor da Silva, Milene Costa Bañobre-López, Manuel Gallo, Juan Int J Mol Sci Review Polymeric materials have been extensively explored in the field of nanomedicine; within them, poly lactic-co-glycolic acid (PLGA) holds a prominent position in micro- and nanotechnology due to its biocompatibility and controllable biodegradability. In this review we focus on the combination of PLGA with different inorganic nanomaterials in the form of nanocomposites to overcome the polymer’s limitations and extend its field of applications. We discuss their physicochemical properties and a variety of well-established synthesis methods for the preparation of different PLGA-based materials. Recent progress in the design and biomedical applications of PLGA-based materials are thoroughly discussed to provide a framework for future research. MDPI 2022-02-12 /pmc/articles/PMC8876940/ /pubmed/35216149 http://dx.doi.org/10.3390/ijms23042034 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Rocha, Cátia Vieira
Gonçalves, Victor
da Silva, Milene Costa
Bañobre-López, Manuel
Gallo, Juan
PLGA-Based Composites for Various Biomedical Applications
title PLGA-Based Composites for Various Biomedical Applications
title_full PLGA-Based Composites for Various Biomedical Applications
title_fullStr PLGA-Based Composites for Various Biomedical Applications
title_full_unstemmed PLGA-Based Composites for Various Biomedical Applications
title_short PLGA-Based Composites for Various Biomedical Applications
title_sort plga-based composites for various biomedical applications
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8876940/
https://www.ncbi.nlm.nih.gov/pubmed/35216149
http://dx.doi.org/10.3390/ijms23042034
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