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PLGA-Based Composites for Various Biomedical Applications
Polymeric materials have been extensively explored in the field of nanomedicine; within them, poly lactic-co-glycolic acid (PLGA) holds a prominent position in micro- and nanotechnology due to its biocompatibility and controllable biodegradability. In this review we focus on the combination of PLGA...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8876940/ https://www.ncbi.nlm.nih.gov/pubmed/35216149 http://dx.doi.org/10.3390/ijms23042034 |
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author | Rocha, Cátia Vieira Gonçalves, Victor da Silva, Milene Costa Bañobre-López, Manuel Gallo, Juan |
author_facet | Rocha, Cátia Vieira Gonçalves, Victor da Silva, Milene Costa Bañobre-López, Manuel Gallo, Juan |
author_sort | Rocha, Cátia Vieira |
collection | PubMed |
description | Polymeric materials have been extensively explored in the field of nanomedicine; within them, poly lactic-co-glycolic acid (PLGA) holds a prominent position in micro- and nanotechnology due to its biocompatibility and controllable biodegradability. In this review we focus on the combination of PLGA with different inorganic nanomaterials in the form of nanocomposites to overcome the polymer’s limitations and extend its field of applications. We discuss their physicochemical properties and a variety of well-established synthesis methods for the preparation of different PLGA-based materials. Recent progress in the design and biomedical applications of PLGA-based materials are thoroughly discussed to provide a framework for future research. |
format | Online Article Text |
id | pubmed-8876940 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-88769402022-02-26 PLGA-Based Composites for Various Biomedical Applications Rocha, Cátia Vieira Gonçalves, Victor da Silva, Milene Costa Bañobre-López, Manuel Gallo, Juan Int J Mol Sci Review Polymeric materials have been extensively explored in the field of nanomedicine; within them, poly lactic-co-glycolic acid (PLGA) holds a prominent position in micro- and nanotechnology due to its biocompatibility and controllable biodegradability. In this review we focus on the combination of PLGA with different inorganic nanomaterials in the form of nanocomposites to overcome the polymer’s limitations and extend its field of applications. We discuss their physicochemical properties and a variety of well-established synthesis methods for the preparation of different PLGA-based materials. Recent progress in the design and biomedical applications of PLGA-based materials are thoroughly discussed to provide a framework for future research. MDPI 2022-02-12 /pmc/articles/PMC8876940/ /pubmed/35216149 http://dx.doi.org/10.3390/ijms23042034 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Rocha, Cátia Vieira Gonçalves, Victor da Silva, Milene Costa Bañobre-López, Manuel Gallo, Juan PLGA-Based Composites for Various Biomedical Applications |
title | PLGA-Based Composites for Various Biomedical Applications |
title_full | PLGA-Based Composites for Various Biomedical Applications |
title_fullStr | PLGA-Based Composites for Various Biomedical Applications |
title_full_unstemmed | PLGA-Based Composites for Various Biomedical Applications |
title_short | PLGA-Based Composites for Various Biomedical Applications |
title_sort | plga-based composites for various biomedical applications |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8876940/ https://www.ncbi.nlm.nih.gov/pubmed/35216149 http://dx.doi.org/10.3390/ijms23042034 |
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