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Splenic Architecture and Function Requires Tight Control of Transmembrane TNF Expression

Soluble tumor necrosis factor (sTNF) is an important inflammatory mediator and essential for secondary lymphoid organ (SLO) development and function. However, the role of its transmembrane counterpart (tmTNF) in these processes is less well established. Here, the effects of tmTNF overxpression on SL...

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Detalles Bibliográficos
Autores principales: Jeucken, Kim C. M., Kaaij, Merlijn H., Rip, Jasper, van Rooijen, Charlotte C. N., Kan, Yik Y., Corneth, Odilia B. J., van Hamburg, Jan Piet, Tas, Sander W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8876982/
https://www.ncbi.nlm.nih.gov/pubmed/35216345
http://dx.doi.org/10.3390/ijms23042229