Cargando…

Splenic Architecture and Function Requires Tight Control of Transmembrane TNF Expression

Soluble tumor necrosis factor (sTNF) is an important inflammatory mediator and essential for secondary lymphoid organ (SLO) development and function. However, the role of its transmembrane counterpart (tmTNF) in these processes is less well established. Here, the effects of tmTNF overxpression on SL...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jeucken, Kim C. M., Kaaij, Merlijn H., Rip, Jasper, van Rooijen, Charlotte C. N., Kan, Yik Y., Corneth, Odilia B. J., van Hamburg, Jan Piet, Tas, Sander W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8876982/ https://www.ncbi.nlm.nih.gov/pubmed/35216345 http://dx.doi.org/10.3390/ijms23042229

Ejemplares similares

A Straightforward Method for 3D Visualization of B Cell Clusters and High Endothelial Venules in Lymph Nodes Highlights Differential Roles of TNFRI and -II
por: Jeucken, Kim C. M., et al.
Publicado: (2021)

Transmembrane TNF drives osteoproliferative joint inflammation reminiscent of human spondyloarthritis
por: Kaaij, Merlijn H., et al.
Publicado: (2020)

Differential Contribution of NF-κB Signaling Pathways to CD4(+) Memory T Cell Induced Activation of Endothelial Cells
por: Jeucken, Kim C. M., et al.
Publicado: (2022)

Bruton’s Tyrosine Kinase Inhibition as an Emerging Therapy in Systemic Autoimmune Disease
por: Neys, Stefan F. H., et al.
Publicado: (2021)

The Role of Endothelial Cells and TNF-Receptor Superfamily Members in Lymphoid Organogenesis and Function During Health and Inflammation
por: Jeucken, Kim C. M., et al.
Publicado: (2019)

Aberrant B Cell Receptor Signaling in Naïve B Cells from Patients with Idiopathic Pulmonary Fibrosis
por: Neys, Stefan F. H., et al.
Publicado: (2021)

Toll-Like Receptor Signaling Drives Btk-Mediated Autoimmune Disease
por: Rip, Jasper, et al.
Publicado: (2019)

Editorial for Special Issue “Advances in the Pathogenesis and Treatment of Immune-Mediated Inflammatory Diseases”
por: van Hamburg, Jan Piet, et al.
Publicado: (2022)

Bruton's tyrosine kinase inhibition induces rewiring of proximal and distal B‐cell receptor signaling in mice
por: Rip, Jasper, et al.
Publicado: (2021)

A novel 3D spheroid model of rheumatoid arthritis synovial tissue incorporating fibroblasts, endothelial cells, and macrophages
por: Philippon, Eva M. L., et al.
Publicado: (2023)

B Lineage Cells in ANCA-Associated Vasculitis
por: Merino-Vico, Ana, et al.
Publicado: (2021)

Transmembrane TNF-dependent uptake of anti-TNF antibodies
por: Deora, Arun, et al.
Publicado: (2017)

Evidence for enhanced Bruton’s tyrosine kinase activity in transitional and naïve B cells of patients with granulomatosis with polyangiitis
por: von Borstel, Anouk, et al.
Publicado: (2019)

Anti-IL-17A treatment reduces serum inflammatory, angiogenic and tissue remodeling biomarkers accompanied by less synovial high endothelial venules in peripheral spondyloarthritis
por: Kaaij, Merlijn H., et al.
Publicado: (2020)

B Cell Signaling and Activation in Autoimmunity
por: Hendriks, Rudi W., et al.
Publicado: (2023)

Targeting B cells and plasma cells in autoimmune diseases: From established treatments to novel therapeutic approaches
por: Merino‐Vico, Ana, et al.
Publicado: (2022)

Transmembrane TNF-α: structure, function and interaction with anti-TNF agents
por: Horiuchi, Takahiko, et al.
Publicado: (2010)

The Diversity and Similarity of Transmembrane Trimerization of TNF Receptors
por: Zhao, Linlin, et al.
Publicado: (2020)

Response to ‘T-helper 17 cell cytokines and interferon type I: partners in crime in systemic lupus erythematosus?’ – Authors’ reply
por: Brkic, Zana, et al.
Publicado: (2014)

Specific Remodeling of Splenic Architecture by Cytomegalovirus
por: Benedict, Chris A, et al.
Publicado: (2006)

Human T-bet(+) B cell development is associated with BTK activity and suppressed by evobrutinib
por: Rijvers, Liza, et al.
Publicado: (2022)

Targeting Bruton’s Tyrosine Kinase in Inflammatory and Autoimmune Pathologies
por: Neys, Stefan F. H., et al.
Publicado: (2021)

Aberrant B Cell Signaling in Autoimmune Diseases
por: Corneth, Odilia B. J., et al.
Publicado: (2022)

Methotrexate Enhances Apoptosis of Transmembrane TNF-Expressing Cells Treated With Anti-TNF Agents
por: Wang, Qiaolei, et al.
Publicado: (2020)

Splenic abscesses complicating acute septicemic melioidosis
por: Chang, Chee Yik
Publicado: (2023)

T-helper 17 cell cytokines and interferon type I: partners in crime in systemic lupus erythematosus?
por: Brkic, Zana, et al.
Publicado: (2014)

Transmembrane TNF-alpha promotes chemoresistance in breast cancer cells
por: Zhang, Zunyue, et al.
Publicado: (2018)

Bedside ultrasonography for rapid detection of splenic abscess in melioidosis
por: Chang, Chee Yik
Publicado: (2023)

The location of splenic NKT cells favours their rapid activation by blood-borne antigen
por: Barral, Patricia, et al.
Publicado: (2012)

Identification of MarvelD3 as a tight junction-associated transmembrane protein of the occludin family
por: Steed, Emily, et al.
Publicado: (2009)

IL-23 Dependent and Independent Stages of Experimental Arthritis: No Clinical Effect of Therapeutic IL-23p19 Inhibition in Collagen-induced Arthritis
por: Cornelissen, Ferry, et al.
Publicado: (2013)

Systemic Loss and Gain of Chromatin Architecture throughout Zebrafish Development
por: Kaaij, Lucas J.T., et al.
Publicado: (2018)

Nano-scale architecture of blood-brain barrier tight-junctions
por: Sasson, Esther, et al.
Publicado: (2021)

Architecture of Dispatched, a Transmembrane Protein Responsible for Hedgehog Release
por: Luo, Yitian, et al.
Publicado: (2021)

The architecture of transmembrane and cytoplasmic juxtamembrane regions of Toll-like receptors
por: Kornilov, F. D., et al.
Publicado: (2023)

Spontaneous splenic rupture in Plasmodium knowlesi malaria
por: Chang, Chee Yik, et al.
Publicado: (2018)

Transmembrane TNF and Its Receptors TNFR1 and TNFR2 in Mycobacterial Infections
por: Ruiz, Andy, et al.
Publicado: (2021)

Deep Profiling of Mouse Splenic Architecture with CODEX Multiplexed Imaging
por: Goltsev, Yury, et al.
Publicado: (2018)

Transmembrane TNF-α Density, but not Soluble TNF-α Level, is Associated with Primary Response to Infliximab in Inflammatory Bowel Disease
por: Amini Kadijani, Azade, et al.
Publicado: (2017)

Silencing NIK potentiates anti-VEGF therapy in a novel 3D model of colorectal cancer angiogenesis
por: Maracle, Chrissta X., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_8321g0ju01ouhslitdhappdret