Michael Addition of 3-Oxo-3-phenylpropanenitrile to Linear Conjugated Enynones: Approach to Polyfunctional δ-Diketones as Precursors for Heterocycle Synthesis

Reaction of linear conjugated enynones, 1,5-diarylpent-2-en-4-yn-1-ones [Ar(1)C≡CCH=CHC(=O)Ar(2)], with 3-oxo-3-phenylpropanenitrile (NCCH(2)COPh) in the presence of sodium methoxide MeONa as a base in MeOH at room temperature for 4–26 h affords polyfunctional δ-diketones as a product of regioselect...

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Detalles Bibliográficos
Autores principales: Igushkina, Anastasiya V., Golovanov, Alexander A., Vasilyev, Aleksander V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8877045/
https://www.ncbi.nlm.nih.gov/pubmed/35209045
http://dx.doi.org/10.3390/molecules27041256

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8877045/
https://www.ncbi.nlm.nih.gov/pubmed/35209045
http://dx.doi.org/10.3390/molecules27041256

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