Cargando…

Amphiphilic Anionic Oligomer-Stabilized Calcium Phosphate Nanoparticles with Prospects in siRNA Delivery via Convection-Enhanced Delivery

Convection-enhanced delivery (CED) has been introduced as a concept in cancer treatment to generate high local concentrations of anticancer therapeutics and overcome the limited diffusional distribution, e.g., in the brain. RNA interference provides interesting therapeutic options to fight cancer ce...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mitrach, Franziska, Schmid, Maximilian, Toussaint, Magali, Dukic-Stefanovic, Sladjana, Deuther-Conrad, Winnie, Franke, Heike, Ewe, Alexander, Aigner, Achim, Wölk, Christian, Brust, Peter, Hacker, Michael C., Schulz-Siegmund, Michaela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8877163/ https://www.ncbi.nlm.nih.gov/pubmed/35214058 http://dx.doi.org/10.3390/pharmaceutics14020326

Ejemplares similares

Synthesis and Biological Evaluation of a Novel (18)F-Labeled Radiotracer for PET Imaging of the Adenosine A(2A) Receptor
por: Lai, Thu Hang, et al.
Publicado: (2021)

Mineralizing Gelatin Microparticles as Cell Carrier and Drug Delivery System for siRNA for Bone Tissue Engineering
por: Hinkelmann, Sandra, et al.
Publicado: (2022)

Radiosynthesis and Biological Investigation of a Novel Fluorine-18 Labeled Benzoimidazotriazine-Based Radioligand for the Imaging of Phosphodiesterase 2A with Positron Emission Tomography
por: Ritawidya, Rien, et al.
Publicado: (2019)

Development of (18)F-Labeled Radiotracers for PET Imaging of the Adenosine A(2A) Receptor: Synthesis, Radiolabeling and Preliminary Biological Evaluation
por: Lai, Thu Hang, et al.
Publicado: (2021)

Development of a Radiofluorinated Adenosine A(2B) Receptor Antagonist as Potential Ligand for PET Imaging
por: Lindemann, Marcel, et al.
Publicado: (2020)

Non-Invasive Assessment of Locally Overexpressed Human Adenosine 2A Receptors in the Heart of Transgenic Mice
por: Gündel, Daniel, et al.
Publicado: (2022)

Amphiphilic Peptides for Efficient siRNA Delivery
por: Mozaffari, Saghar, et al.
Publicado: (2019)

PET Imaging of the Adenosine A(2A) Receptor in the Rotenone-Based Mouse Model of Parkinson’s Disease with [(18)F]FESCH Synthesized by a Simplified Two-Step One-Pot Radiolabeling Strategy
por: Schröder, Susann, et al.
Publicado: (2020)

Development and Biological Evaluation of the First Highly Potent and Specific Benzamide-Based Radiotracer [(18)F]BA3 for Imaging of Histone Deacetylases 1 and 2 in Brain
por: Clauß, Oliver, et al.
Publicado: (2022)

Polymeric Nanoparticles Based on Tyrosine-Modified, Low Molecular Weight Polyethylenimines for siRNA Delivery
por: Ewe, Alexander, et al.
Publicado: (2019)

Improved in vivo PET imaging of the adenosine A(2A) receptor in the brain using [(18)F]FLUDA, a deuterated radiotracer with high metabolic stability
por: Lai, Thu Hang, et al.
Publicado: (2021)

Synthesis of Novel Fluorinated Xanthine Derivatives with High Adenosine A(2B) Receptor Binding Affinity
por: Lindemann, Marcel, et al.
Publicado: (2021)

Amphiphilic Polypeptides for VEGF siRNA Delivery into Retinal Epithelial Cells
por: Osipova, Olga, et al.
Publicado: (2020)

Development of a New Radiofluorinated Quinoline Analog for PET Imaging of Phosphodiesterase 5 (PDE5) in Brain
por: Liu, Jianrong, et al.
Publicado: (2016)

Albumin pre-coating enhances intracellular siRNA delivery of multifunctional amphiphile/siRNA nanoparticles
por: Kummitha, China M, et al.
Publicado: (2012)

Cationic and PEGylated Amphiphilic Cyclodextrins: Co-Formulation Opportunities for Neuronal Sirna Delivery
por: O’Mahony, Aoife M., et al.
Publicado: (2013)

Screening Nylon-3 Polymers, a New Class of Cationic Amphiphiles, for siRNA Delivery
por: Nadithe, Venkatareddy, et al.
Publicado: (2014)

Synthesis and application of spermine-based amphiphilic poly(β-amino ester)s for siRNA delivery
por: Jin, Yao, et al.
Publicado: (2023)

Non-Covalent Associates of siRNAs and AuNPs Enveloped with Lipid Layer and Doped with Amphiphilic Peptide for Efficient siRNA Delivery
por: Poletaeva, Julia, et al.
Publicado: (2018)

Development of [(18)F]LU14 for PET Imaging of Cannabinoid Receptor Type 2 in the Brain
por: Teodoro, Rodrigo, et al.
Publicado: (2021)

Radiosynthesis and Preclinical Evaluation of an (18)F-Labeled Triazolopyridopyrazine-Based Inhibitor for Neuroimaging of the Phosphodiesterase 2A (PDE2A)
por: Wenzel, Barbara, et al.
Publicado: (2022)

Delivery Systems for the Direct Application of siRNAs to Induce RNA Interference (RNAi) In Vivo
por: Aigner, Achim
Publicado: (2006)

Convection-enhanced drug delivery for gliomas
por: Healy, Andrew T., et al.
Publicado: (2015)

Gene delivery based on macrocyclic amphiphiles
por: Geng, Wen-Chao, et al.
Publicado: (2019)

AKT2 siRNA delivery with amphiphilic-based polymeric micelles show efficacy against cancer stem cells
por: Rafael, Diana, et al.
Publicado: (2018)

Co-Formulation of Amphiphilic Cationic and Anionic Cyclodextrins Forming Nanoparticles for siRNA Delivery in the Treatment of Acute Myeloid Leukaemia
por: Kont, Ayse, et al.
Publicado: (2022)

Amphiphilic Polypeptides Obtained by Post-Polymerization Modification of Poly-l-Lysine as Systems for Combined Delivery of Paclitaxel and siRNA
por: Dzhuzha, Apollinariia, et al.
Publicado: (2023)

Newly Synthesized Fluorinated Cinnamylpiperazines Possessing Low In Vitro MAO-B Binding
por: I. Jevtić, Ivana, et al.
Publicado: (2020)

Convection-Enhanced Delivery for Targeted Delivery of Antiglioma Agents: The Translational Experience
por: Yun, Jonathan, et al.
Publicado: (2013)

Tyrosine-Modification of Polypropylenimine (PPI) and Polyethylenimine (PEI) Strongly Improves Efficacy of siRNA-Mediated Gene Knockdown
por: Noske, Sandra, et al.
Publicado: (2020)

Imaging of Convection Enhanced Delivery of Toxins in Humans
por: Mehta, Ankit I., et al.
Publicado: (2011)

Convection-enhanced Delivery of Therapeutics for Malignant Gliomas
por: SAITO, Ryuta, et al.
Publicado: (2017)

Convection-enhanced Drug Delivery for Glioblastoma: A Systematic Review Focused on Methodological Differences in the Use of the Convection-enhanced Delivery Method
por: Halle, Bo, et al.
Publicado: (2019)

Targeted Delivery of siRNA
por: Oliveira, Sabrina, et al.
Publicado: (2006)

Dendrimers for siRNA Delivery
por: Biswas, Swati, et al.
Publicado: (2013)

Design, Radiosynthesis and Preliminary Biological Evaluation in Mice of a Brain-Penetrant (18)F-Labelled σ(2) Receptor Ligand
por: Moldovan, Rareş-Petru, et al.
Publicado: (2021)

Novel Radioiodinated and Radiofluorinated Analogues of FT-2102 for SPECT or PET Imaging of mIDH1 Mutant Tumours
por: Weber, Valérie, et al.
Publicado: (2022)

Convection and Retro-Convection Enhanced Delivery: Some Theoretical Considerations Related to Drug Targeting
por: Motion, J. P. Michael, et al.
Publicado: (2010)

Microtissues from mesenchymal stem cells and siRNA-loaded cross-linked gelatin microparticles for bone regeneration
por: Hinkelmann, Sandra, et al.
Publicado: (2021)

Convection-enhanced delivery of methotrexate-loaded maghemite nanoparticles
por: Corem-Salkmon, Enav, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_78ulded2af96fcr2bblq6q0eli