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The Hydrophobicity and Antifungal Potentiation of Burkholdine Analogues

The burkholdines are a family of cyclic lipopeptides reported to exhibit antifungal activity. We synthesized a series of 18 burkholdine analogues in good yield by conventional Fmoc-SPPS followed by cyclization with DIPCI/HOBt in the solution phase. Although none of the synthesized peptides exhibited...

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Detalles Bibliográficos
Autores principales:	Konno, Hiroyuki, Sasaki, Mio, Sano, Hinata, Osawa, Keima, Nosaka, Kazuto, Yano, Shigekazu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8877233/ https://www.ncbi.nlm.nih.gov/pubmed/35208979 http://dx.doi.org/10.3390/molecules27041191

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