A Lead-Based Fragment Library Screening of the Glycosyltransferase WaaG from Escherichia coli

Glucosyl transferase I (WaaG) in E. coli catalyzes the transfer of an α-d-glucosyl group to the inner core of the lipopolysaccharide (LPS) and plays an important role in the biogenesis of the outer membrane. If its activity could be inhibited, the integrity of the outer membrane would be compromised...

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Detalles Bibliográficos
Autores principales: Riu, Federico, Ruda, Alessandro, Engström, Olof, Muheim, Claudio, Mobarak, Hani, Ståhle, Jonas, Kosma, Paul, Carta, Antonio, Daley, Daniel O., Widmalm, Göran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8877264/
https://www.ncbi.nlm.nih.gov/pubmed/35215321
http://dx.doi.org/10.3390/ph15020209

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