Hexokinase-2-Linked Glycolytic Overload and Unscheduled Glycolysis—Driver of Insulin Resistance and Development of Vascular Complications of Diabetes

The recent discovery of the glucose-induced stabilization of hexokinase-2 (HK2) to proteolysis in cell dysfunction in model hyperglycemia has revealed a likely key initiating factor contributing to the development of insulin resistance and vascular complications in diabetes. Consequently, the increa...

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Detalles Bibliográficos
Autores principales: Rabbani, Naila, Xue, Mingzhan, Thornalley, Paul J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8877341/
https://www.ncbi.nlm.nih.gov/pubmed/35216280
http://dx.doi.org/10.3390/ijms23042165

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8877341/
https://www.ncbi.nlm.nih.gov/pubmed/35216280
http://dx.doi.org/10.3390/ijms23042165

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