A Monolithic 3D Printed Axisymmetric Co-Flow Single and Compound Emulsion Generator

We report a microfluidic droplet generator which can produce single and compound droplets using a 3D axisymmetric co-flow structure. The design considered for the fabrication of the device integrated a user-friendly and cost-effective 3D printing process. To verify the performance of the device, sin...

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Autores principales: Ghaznavi, Amirreza, Lin, Yang, Douvidzon, Mark, Szmelter, Adam, Rodrigues, Alannah, Blackman, Malik, Eddington, David, Carmon, Tal, Deych, Lev, Yang, Lan, Xu, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8877394/
https://www.ncbi.nlm.nih.gov/pubmed/35208313
http://dx.doi.org/10.3390/mi13020188
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author Ghaznavi, Amirreza
Lin, Yang
Douvidzon, Mark
Szmelter, Adam
Rodrigues, Alannah
Blackman, Malik
Eddington, David
Carmon, Tal
Deych, Lev
Yang, Lan
Xu, Jie
author_facet Ghaznavi, Amirreza
Lin, Yang
Douvidzon, Mark
Szmelter, Adam
Rodrigues, Alannah
Blackman, Malik
Eddington, David
Carmon, Tal
Deych, Lev
Yang, Lan
Xu, Jie
author_sort Ghaznavi, Amirreza
collection PubMed
description We report a microfluidic droplet generator which can produce single and compound droplets using a 3D axisymmetric co-flow structure. The design considered for the fabrication of the device integrated a user-friendly and cost-effective 3D printing process. To verify the performance of the device, single and compound emulsions of deionized water and mineral oil were generated and their features such as size, generation frequency, and emulsion structures were successfully characterized. In addition, the generation of bio emulsions such as alginate and collagen aqueous droplets in mineral oil was demonstrated in this study. Overall, the monolithic 3D printed axisymmetric droplet generator could offer any user an accessible and easy-to-utilize device for the generation of single and compound emulsions.
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spelling pubmed-88773942022-02-26 A Monolithic 3D Printed Axisymmetric Co-Flow Single and Compound Emulsion Generator Ghaznavi, Amirreza Lin, Yang Douvidzon, Mark Szmelter, Adam Rodrigues, Alannah Blackman, Malik Eddington, David Carmon, Tal Deych, Lev Yang, Lan Xu, Jie Micromachines (Basel) Article We report a microfluidic droplet generator which can produce single and compound droplets using a 3D axisymmetric co-flow structure. The design considered for the fabrication of the device integrated a user-friendly and cost-effective 3D printing process. To verify the performance of the device, single and compound emulsions of deionized water and mineral oil were generated and their features such as size, generation frequency, and emulsion structures were successfully characterized. In addition, the generation of bio emulsions such as alginate and collagen aqueous droplets in mineral oil was demonstrated in this study. Overall, the monolithic 3D printed axisymmetric droplet generator could offer any user an accessible and easy-to-utilize device for the generation of single and compound emulsions. MDPI 2022-01-26 /pmc/articles/PMC8877394/ /pubmed/35208313 http://dx.doi.org/10.3390/mi13020188 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Ghaznavi, Amirreza
Lin, Yang
Douvidzon, Mark
Szmelter, Adam
Rodrigues, Alannah
Blackman, Malik
Eddington, David
Carmon, Tal
Deych, Lev
Yang, Lan
Xu, Jie
A Monolithic 3D Printed Axisymmetric Co-Flow Single and Compound Emulsion Generator
title A Monolithic 3D Printed Axisymmetric Co-Flow Single and Compound Emulsion Generator
title_full A Monolithic 3D Printed Axisymmetric Co-Flow Single and Compound Emulsion Generator
title_fullStr A Monolithic 3D Printed Axisymmetric Co-Flow Single and Compound Emulsion Generator
title_full_unstemmed A Monolithic 3D Printed Axisymmetric Co-Flow Single and Compound Emulsion Generator
title_short A Monolithic 3D Printed Axisymmetric Co-Flow Single and Compound Emulsion Generator
title_sort monolithic 3d printed axisymmetric co-flow single and compound emulsion generator
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8877394/
https://www.ncbi.nlm.nih.gov/pubmed/35208313
http://dx.doi.org/10.3390/mi13020188
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