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Cooperative Chikungunya Virus Membrane Fusion and Its Substoichiometric Inhibition by CHK-152 Antibody

Chikungunya virus (CHIKV) presents a major burden on healthcare systems worldwide, but specific treatment remains unavailable. Attachment and fusion of CHIKV to the host cell membrane is mediated by the E1/E2 protein spikes. We used an in vitro single-particle fusion assay to study the effect of the...

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Detalles Bibliográficos
Autores principales:	Blijleven, Jelle S., Bouma, Ellen M., van Duijl-Richter, Mareike K. S., Smit, Jolanda M., van Oijen, Antoine M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8877538/ https://www.ncbi.nlm.nih.gov/pubmed/35215863 http://dx.doi.org/10.3390/v14020270

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