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Inhibiting CK2 among Promising Therapeutic Strategies for Gliomas and Several Other Neoplasms
In gliomas, casein kinase 2 (CK2) plays a dominant role in cell survival and tumour invasiveness and is upregulated in many brain tumours. Among CK2 inhibitors, benzimidazole and isothiourea derivatives hold a dominant position. While targeting glioma tumour cells, they show limited toxicity towards...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8877581/ https://www.ncbi.nlm.nih.gov/pubmed/35214064 http://dx.doi.org/10.3390/pharmaceutics14020331 |