Cargando…
Clinical and Electrocardiographic Findings for Predicting the Severity of Pulmonary Valve Stenosis in Dogs
Pulmonary valve stenosis (PS) in dogs is usually suspected due to the presence of a heart murmur and clinical signs. Echocardiography is needed to confirm the diagnosis and define the severity of PS. This retrospective study evaluated the utility of clinical and electrocardiographic (ECG) findings i...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8877586/ https://www.ncbi.nlm.nih.gov/pubmed/35202314 http://dx.doi.org/10.3390/vetsci9020061 |
_version_ | 1784658456056168448 |
---|---|
author | Bini, Martina Vezzosi, Tommaso Fernández Del Palacio, Maria Josefa Talavera, Jesús Patata, Valentina Marchesotti, Federica Domenech, Oriol |
author_facet | Bini, Martina Vezzosi, Tommaso Fernández Del Palacio, Maria Josefa Talavera, Jesús Patata, Valentina Marchesotti, Federica Domenech, Oriol |
author_sort | Bini, Martina |
collection | PubMed |
description | Pulmonary valve stenosis (PS) in dogs is usually suspected due to the presence of a heart murmur and clinical signs. Echocardiography is needed to confirm the diagnosis and define the severity of PS. This retrospective study evaluated the utility of clinical and electrocardiographic (ECG) findings in the prediction of PS severity. Data regarding heart murmur and ECG analysis were gathered. Ninety-seven dogs with PS were included. A murmur grade ≥IV/VI was predictive of severe PS (area under curve (AUC) = 0.71; sensitivity (Se) = 95%; specificity (Sp) = 33%; p = 0.003). In lead II, P wave amplitude >0.35 mV (AUC = 0.67; Se = 31%; Sp = 100%; p = 0.038), Q wave < 0.15 mV (AUC = 0.70; Se = 70%; Sp = 59%; p = 0.0015), R wave < 0.87 mV (AUC = 0.66; Se = 67%; Sp = 69%; p = 0.006), and S wave > 0.37 mV (AUC = 0.80; Se = 72%; Sp = 85%; p < 0.0001) were predictive of severe PS. The extent of right deviation of the mean electrical axis of the QRS complex was correlated with the pulmonary pressure gradient (r = 0.648; p < 0.0001). In conclusion, a systolic murmur with intensity ≥IV/VI, a P wave amplitude >0.35 mV, low amplitude of Q and R waves, deep S waves in lead II, and right axis deviation of the QRS complex in a young dog are predictive of severe PS. |
format | Online Article Text |
id | pubmed-8877586 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-88775862022-02-26 Clinical and Electrocardiographic Findings for Predicting the Severity of Pulmonary Valve Stenosis in Dogs Bini, Martina Vezzosi, Tommaso Fernández Del Palacio, Maria Josefa Talavera, Jesús Patata, Valentina Marchesotti, Federica Domenech, Oriol Vet Sci Article Pulmonary valve stenosis (PS) in dogs is usually suspected due to the presence of a heart murmur and clinical signs. Echocardiography is needed to confirm the diagnosis and define the severity of PS. This retrospective study evaluated the utility of clinical and electrocardiographic (ECG) findings in the prediction of PS severity. Data regarding heart murmur and ECG analysis were gathered. Ninety-seven dogs with PS were included. A murmur grade ≥IV/VI was predictive of severe PS (area under curve (AUC) = 0.71; sensitivity (Se) = 95%; specificity (Sp) = 33%; p = 0.003). In lead II, P wave amplitude >0.35 mV (AUC = 0.67; Se = 31%; Sp = 100%; p = 0.038), Q wave < 0.15 mV (AUC = 0.70; Se = 70%; Sp = 59%; p = 0.0015), R wave < 0.87 mV (AUC = 0.66; Se = 67%; Sp = 69%; p = 0.006), and S wave > 0.37 mV (AUC = 0.80; Se = 72%; Sp = 85%; p < 0.0001) were predictive of severe PS. The extent of right deviation of the mean electrical axis of the QRS complex was correlated with the pulmonary pressure gradient (r = 0.648; p < 0.0001). In conclusion, a systolic murmur with intensity ≥IV/VI, a P wave amplitude >0.35 mV, low amplitude of Q and R waves, deep S waves in lead II, and right axis deviation of the QRS complex in a young dog are predictive of severe PS. MDPI 2022-02-01 /pmc/articles/PMC8877586/ /pubmed/35202314 http://dx.doi.org/10.3390/vetsci9020061 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Bini, Martina Vezzosi, Tommaso Fernández Del Palacio, Maria Josefa Talavera, Jesús Patata, Valentina Marchesotti, Federica Domenech, Oriol Clinical and Electrocardiographic Findings for Predicting the Severity of Pulmonary Valve Stenosis in Dogs |
title | Clinical and Electrocardiographic Findings for Predicting the Severity of Pulmonary Valve Stenosis in Dogs |
title_full | Clinical and Electrocardiographic Findings for Predicting the Severity of Pulmonary Valve Stenosis in Dogs |
title_fullStr | Clinical and Electrocardiographic Findings for Predicting the Severity of Pulmonary Valve Stenosis in Dogs |
title_full_unstemmed | Clinical and Electrocardiographic Findings for Predicting the Severity of Pulmonary Valve Stenosis in Dogs |
title_short | Clinical and Electrocardiographic Findings for Predicting the Severity of Pulmonary Valve Stenosis in Dogs |
title_sort | clinical and electrocardiographic findings for predicting the severity of pulmonary valve stenosis in dogs |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8877586/ https://www.ncbi.nlm.nih.gov/pubmed/35202314 http://dx.doi.org/10.3390/vetsci9020061 |
work_keys_str_mv | AT binimartina clinicalandelectrocardiographicfindingsforpredictingtheseverityofpulmonaryvalvestenosisindogs AT vezzositommaso clinicalandelectrocardiographicfindingsforpredictingtheseverityofpulmonaryvalvestenosisindogs AT fernandezdelpalaciomariajosefa clinicalandelectrocardiographicfindingsforpredictingtheseverityofpulmonaryvalvestenosisindogs AT talaverajesus clinicalandelectrocardiographicfindingsforpredictingtheseverityofpulmonaryvalvestenosisindogs AT patatavalentina clinicalandelectrocardiographicfindingsforpredictingtheseverityofpulmonaryvalvestenosisindogs AT marchesottifederica clinicalandelectrocardiographicfindingsforpredictingtheseverityofpulmonaryvalvestenosisindogs AT domenechoriol clinicalandelectrocardiographicfindingsforpredictingtheseverityofpulmonaryvalvestenosisindogs |