Cargando…

CHRNA5 Contributes to Hepatocellular Carcinoma Progression by Regulating YAP Activity

Hepatocellular carcinoma (HCC) is a major health concern worldwide. A better understanding of the mechanisms underlying the malignant phenotype is necessary for developing novel therapeutic strategies for HCC. Signaling pathways initiated by neurotransmitter receptors, such as α5-nicotinic acetylcho...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fu, Yan, Ci, Hongfei, Du, Wei, Dong, Qiongzhu, Jia, Huliang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8877699/ https://www.ncbi.nlm.nih.gov/pubmed/35214008 http://dx.doi.org/10.3390/pharmaceutics14020275

Ejemplares similares

An Angiogenic Gene Signature for Prediction of the Prognosis and Therapeutic Responses of Hepatocellular Carcinoma
por: Ci, Hongfei, et al.
Publicado: (2023)

Organ microenvironment affects growth and metastasis of hepatocellular carcinoma via the TGF-β/Smad pathway in mice
por: LI, GUOCAI, et al.
Publicado: (2013)

Differential combinatorial regulatory network analysis related to venous metastasis of hepatocellular carcinoma
por: Zeng, Lingyao, et al.
Publicado: (2012)

In Vitro and Ex Vivo Analysis of CHRNA3 and CHRNA5 Haplotype Expression
por: Doyle, Glenn A., et al.
Publicado: (2011)

From Men to Mice: CHRNA5/CHRNA3, Smoking Behavior and Disease
por: Ware, Jennifer J., et al.
Publicado: (2012)

CHRNA5 and CHRNA3 polymorphism and lung cancer susceptibility in Palestinian population
por: Ayesh, Basim Mohammad, et al.
Publicado: (2018)

Association of Polymorphism CHRNA5 and CHRNA3 Gene in People Addicted to Nicotine
por: Chmielowiec, Krzysztof, et al.
Publicado: (2022)

The association between KLF4 as a tumor suppressor and the prognosis of hepatocellular carcinoma after curative resection
por: Xue, Min, et al.
Publicado: (2020)

Osteopontin promotes epithelial-mesenchymal transition of hepatocellular carcinoma through regulating vimentin
por: Dong, Qiongzhu, et al.
Publicado: (2016)

NUP37, a positive regulator of YAP/TEAD signaling, promotes the progression of hepatocellular carcinoma
por: Luo, Xiaoling, et al.
Publicado: (2017)

CHRNA5/CHRNA3 gene cluster is a risk factor for lumbar disc herniation: a case-control study
por: Yang, Xuejun, et al.
Publicado: (2019)

Chromosome 15q25 (CHRNA3-CHRNA5) Variation Impacts Indirectly on Lung Cancer Risk
por: Wang, Yufei, et al.
Publicado: (2011)

Polymorphisms of CHRNA3 and CHRNA5: Head and neck cancer and cigarette consumption intensity in a Brazilian population
por: Silva, Mariana R., et al.
Publicado: (2019)

Corosolic Acid Inhibits Cancer Progress Through Inactivating YAP in Hepatocellular Carcinoma
por: Jia, Ming, et al.
Publicado: (2020)

Downregulation of CENPK suppresses hepatocellular carcinoma malignant progression through regulating YAP1
por: Wang, Jianlin, et al.
Publicado: (2019)

Genetic variation at CHRNA5-CHRNA3-CHRNB4 interacts with smoking status to influence body mass index
por: Freathy, Rachel M, et al.
Publicado: (2011)

CCN: core regulatory proteins in the microenvironment that affect the metastasis of hepatocellular carcinoma?
por: Jia, Qingan, et al.
Publicado: (2015)

Impact of CHRNA5 polymorphisms on the risk of schizophrenia in the Chinese Han population
por: Zhan, Dafei, et al.
Publicado: (2019)

CHRNA5 rs16969968 and CHRNA3 rs578776 polymorphisms are associated with multiple nicotine dependence phenotypes in Bangladeshi smokers
por: Chaity, Nusrat Islam, et al.
Publicado: (2022)

CHRNA5 polymorphism and susceptibility to lung cancer in a Chinese population
por: Shen, Bo, et al.
Publicado: (2013)

Role of ncRNAs in Hepatocellular Carcinoma
por: Tu, Kangsheng, et al.
Publicado: (2018)

Downregulation of CENPK Suppresses Hepatocellular Carcinoma Malignant Progression through Regulating YAP1 [Corrigendum]
Publicado: (2022)

CD44 promotes hepatocellular carcinoma progression via upregulation of YAP
por: Zhang, Jun, et al.
Publicado: (2021)

Retinal dehydrogenase 5 (RHD5) attenuates metastasis via regulating HIPPO/YAP signaling pathway in Hepatocellular Carcinoma
por: Hu, Hao, et al.
Publicado: (2020)

O015. Evaluation of the genetic polymorphism of the α3 (CHRNA3) and α5 (CHRNA5) nicotinic receptor subunits, in patients with cluster headache
por: Cainazzo, Maria Michela, et al.
Publicado: (2015)

Study on polymorphisms in CHRNA5/CHRNA3/CHRNB4 gene cluster and the associated with the risk of non-small cell lung cancer
por: Sun, Yiting, et al.
Publicado: (2017)

Association Between CHRNA3 and CHRNA5 Nicotine Receptor Subunit Gene Variants and Nicotine Dependence in an Isolated Populationof Kashubians in Poland
por: Kita-Milczarska, Karolina, et al.
Publicado: (2016)

Gene variance in the nicotinic receptor cluster (CHRNA5‐CHRNA3‐CHRNB4) predicts death from cardiopulmonary disease and cancer in smokers
por: Halldén, S., et al.
Publicado: (2015)

Overexpression of YAP 1 contributes to progressive features and poor prognosis of human urothelial carcinoma of the bladder
por: Liu, Jian-Ye, et al.
Publicado: (2013)

NPFFR2 Contributes to the Malignancy of Hepatocellular Carcinoma Development by Activating RhoA/YAP Signaling
por: Shin, Yuna, et al.
Publicado: (2022)

Diacylglycerol lipase alpha promotes hepatocellular carcinoma progression and induces lenvatinib resistance by enhancing YAP activity
por: Yan, Yu-Chuan, et al.
Publicado: (2023)

Associations between Variation in CHRNA5-CHRNA3-CHRNB4, Body Mass Index and Blood Pressure in the Northern Finland Birth Cohort 1966
por: Kaakinen, Marika, et al.
Publicado: (2012)

The Cumulative Effect of Gene–Gene Interactions Between GSTM1, CHRNA3, CHRNA5 and SOD3 Gene Polymorphisms Combined with Smoking on COPD Risk
por: Ganbold, Chimedlkhamsuren, et al.
Publicado: (2021)

Serotonin and YAP/VGLL4 Balance Correlated with Progression and Poor Prognosis of Hepatocellular Carcinoma
por: Shu, Bo, et al.
Publicado: (2018)

Metformin mediates resensitivity to 5-fluorouracil in hepatocellular carcinoma via the suppression of YAP
por: Tian, Yu, et al.
Publicado: (2016)

Nuclear translocation and activation of YAP by hypoxia contributes to the chemoresistance of SN38 in hepatocellular carcinoma cells
por: Dai, Xiao-Yang, et al.
Publicado: (2016)

A novel lncRNA PLK4 up‐regulated by talazoparib represses hepatocellular carcinoma progression by promoting YAP‐mediated cell senescence
por: Jia, Yan, et al.
Publicado: (2020)

YAP/TEAD-induced PRIM1 contributes to the progression and poor prognosis of gastric carcinoma
por: Guo, Zijun, et al.
Publicado: (2023)

Myricetin Suppresses the Propagation of Hepatocellular Carcinoma via Down-Regulating Expression of YAP
por: Li, Minjing, et al.
Publicado: (2019)

CBX2 Regulates Proliferation and Apoptosis via the Phosphorylation of YAP in Hepatocellular Carcinoma
por: Mao, Jiakai, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_d9fnthbjvnbmuk5fprngdeu94g