Cargando…
Critical Appraisal of Guidelines for Antithrombotic Therapy in Atrial Fibrillation Post-Percutaneous Coronary Intervention
OBJECTIVE: In our present study, our objective was to appraise guidelines on antithrombotic therapy in atrial fibrillation post-percutaneous coronary intervention and to explore the differences in treatment practices for better informed decision-making. METHODS: We searched for English language guid...
Autores principales: | , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ubiquity Press
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8877875/ https://www.ncbi.nlm.nih.gov/pubmed/35342701 http://dx.doi.org/10.5334/gh.1104 |
_version_ | 1784658522142670848 |
---|---|
author | Fan, Yongqiang Zhang, Gaoxing Zhang, Zhengzhipeng Zhang, Shaozhao Liu, Menghui Lin, Yifen Huang, Yiquan Zhong, Xiangbin Zhuang, Xiaodong Liao, Xinxue |
author_facet | Fan, Yongqiang Zhang, Gaoxing Zhang, Zhengzhipeng Zhang, Shaozhao Liu, Menghui Lin, Yifen Huang, Yiquan Zhong, Xiangbin Zhuang, Xiaodong Liao, Xinxue |
author_sort | Fan, Yongqiang |
collection | PubMed |
description | OBJECTIVE: In our present study, our objective was to appraise guidelines on antithrombotic therapy in atrial fibrillation post-percutaneous coronary intervention and to explore the differences in treatment practices for better informed decision-making. METHODS: We searched for English language guidelines published between January 2000 and December 2020 at MEDLINE, Embase and websites of guideline organizations. Guidelines with recommendations on antithrombotic regimens for patients with AF undergoing PCI were included. Appraisal of Guidelines for Research and Evaluation II (AGREE II) instrument was applied to assess guidelines. The reporting of conflicts of interest (COI) was evaluated separately by the RIGHT (Reporting Item for Practice Guidelines in Healthcare) checklist as supplementary items. RESULTS: Sixteen guidelines were included, among which 13 (81.25%) were considered as ‘recommended’ and 1 (6.25%) as ‘unrecommended.’ The average scores of guidelines ranged from 55% to 88% (<60% as low quality, 60–70% as sufficient quality, and >70% as good quality). Among the 6 domains of AGREE II, scope and purpose (84%) and editorial independence(87%) were considered to be the fields in which CPGs performed best, evidenced by the highest mean AGREE II scores. The domains in which the reviewed CPGs received the lowest mean scores were stakeholder involvement (63%) and applicability (58%). The intraclass correlation coefficient scores were excellent in each domain. The overall quality of the selected CPGs was optimal, with the highest score in domain ‘scope and purpose’, and the lowest score in the domain ‘applicability.’ The reporting of COI was satisfactory. CONCLUSIONS: For the recommendations on antithrombotic strategies, guidelines with high AGREE II scores still exist discrepancy on the timing and selection. Current guidance documents on the treatment vary in methodological rigor and recommendations are not always consistent. |
format | Online Article Text |
id | pubmed-8877875 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Ubiquity Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-88778752022-03-24 Critical Appraisal of Guidelines for Antithrombotic Therapy in Atrial Fibrillation Post-Percutaneous Coronary Intervention Fan, Yongqiang Zhang, Gaoxing Zhang, Zhengzhipeng Zhang, Shaozhao Liu, Menghui Lin, Yifen Huang, Yiquan Zhong, Xiangbin Zhuang, Xiaodong Liao, Xinxue Glob Heart Original Research OBJECTIVE: In our present study, our objective was to appraise guidelines on antithrombotic therapy in atrial fibrillation post-percutaneous coronary intervention and to explore the differences in treatment practices for better informed decision-making. METHODS: We searched for English language guidelines published between January 2000 and December 2020 at MEDLINE, Embase and websites of guideline organizations. Guidelines with recommendations on antithrombotic regimens for patients with AF undergoing PCI were included. Appraisal of Guidelines for Research and Evaluation II (AGREE II) instrument was applied to assess guidelines. The reporting of conflicts of interest (COI) was evaluated separately by the RIGHT (Reporting Item for Practice Guidelines in Healthcare) checklist as supplementary items. RESULTS: Sixteen guidelines were included, among which 13 (81.25%) were considered as ‘recommended’ and 1 (6.25%) as ‘unrecommended.’ The average scores of guidelines ranged from 55% to 88% (<60% as low quality, 60–70% as sufficient quality, and >70% as good quality). Among the 6 domains of AGREE II, scope and purpose (84%) and editorial independence(87%) were considered to be the fields in which CPGs performed best, evidenced by the highest mean AGREE II scores. The domains in which the reviewed CPGs received the lowest mean scores were stakeholder involvement (63%) and applicability (58%). The intraclass correlation coefficient scores were excellent in each domain. The overall quality of the selected CPGs was optimal, with the highest score in domain ‘scope and purpose’, and the lowest score in the domain ‘applicability.’ The reporting of COI was satisfactory. CONCLUSIONS: For the recommendations on antithrombotic strategies, guidelines with high AGREE II scores still exist discrepancy on the timing and selection. Current guidance documents on the treatment vary in methodological rigor and recommendations are not always consistent. Ubiquity Press 2022-02-23 /pmc/articles/PMC8877875/ /pubmed/35342701 http://dx.doi.org/10.5334/gh.1104 Text en Copyright: © 2022 The Author(s) https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International License (CC-BY 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. See http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Original Research Fan, Yongqiang Zhang, Gaoxing Zhang, Zhengzhipeng Zhang, Shaozhao Liu, Menghui Lin, Yifen Huang, Yiquan Zhong, Xiangbin Zhuang, Xiaodong Liao, Xinxue Critical Appraisal of Guidelines for Antithrombotic Therapy in Atrial Fibrillation Post-Percutaneous Coronary Intervention |
title | Critical Appraisal of Guidelines for Antithrombotic Therapy in Atrial Fibrillation Post-Percutaneous Coronary Intervention |
title_full | Critical Appraisal of Guidelines for Antithrombotic Therapy in Atrial Fibrillation Post-Percutaneous Coronary Intervention |
title_fullStr | Critical Appraisal of Guidelines for Antithrombotic Therapy in Atrial Fibrillation Post-Percutaneous Coronary Intervention |
title_full_unstemmed | Critical Appraisal of Guidelines for Antithrombotic Therapy in Atrial Fibrillation Post-Percutaneous Coronary Intervention |
title_short | Critical Appraisal of Guidelines for Antithrombotic Therapy in Atrial Fibrillation Post-Percutaneous Coronary Intervention |
title_sort | critical appraisal of guidelines for antithrombotic therapy in atrial fibrillation post-percutaneous coronary intervention |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8877875/ https://www.ncbi.nlm.nih.gov/pubmed/35342701 http://dx.doi.org/10.5334/gh.1104 |
work_keys_str_mv | AT fanyongqiang criticalappraisalofguidelinesforantithrombotictherapyinatrialfibrillationpostpercutaneouscoronaryintervention AT zhanggaoxing criticalappraisalofguidelinesforantithrombotictherapyinatrialfibrillationpostpercutaneouscoronaryintervention AT zhangzhengzhipeng criticalappraisalofguidelinesforantithrombotictherapyinatrialfibrillationpostpercutaneouscoronaryintervention AT zhangshaozhao criticalappraisalofguidelinesforantithrombotictherapyinatrialfibrillationpostpercutaneouscoronaryintervention AT liumenghui criticalappraisalofguidelinesforantithrombotictherapyinatrialfibrillationpostpercutaneouscoronaryintervention AT linyifen criticalappraisalofguidelinesforantithrombotictherapyinatrialfibrillationpostpercutaneouscoronaryintervention AT huangyiquan criticalappraisalofguidelinesforantithrombotictherapyinatrialfibrillationpostpercutaneouscoronaryintervention AT zhongxiangbin criticalappraisalofguidelinesforantithrombotictherapyinatrialfibrillationpostpercutaneouscoronaryintervention AT zhuangxiaodong criticalappraisalofguidelinesforantithrombotictherapyinatrialfibrillationpostpercutaneouscoronaryintervention AT liaoxinxue criticalappraisalofguidelinesforantithrombotictherapyinatrialfibrillationpostpercutaneouscoronaryintervention |