Case Report of Cerebral Sinus Thrombosis Related to Immune Thrombotic Thrombocytopenia Following Administration of ChAdOx1 nCoV-19 for Vaccination against COVID-19

Vaccine-induced immune thrombotic thrombocytopenia (VITT) with cerebral venous sinus thrombosis (CVST) has been recently reported after vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We present a case of a patient with fulminant CVST and thrombocytopenia after rece...

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Autores principales: Szypowski, Wojciech, Dębiec, Aleksander, Świstak, Jarosław, Nowocień, Maciej, Rzepecki, Piotr, Możański, Marcin, Staszewski, Jacek, Stępień, Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8877999/
https://www.ncbi.nlm.nih.gov/pubmed/35207456
http://dx.doi.org/10.3390/life12020168
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author Szypowski, Wojciech
Dębiec, Aleksander
Świstak, Jarosław
Nowocień, Maciej
Rzepecki, Piotr
Możański, Marcin
Staszewski, Jacek
Stępień, Adam
author_facet Szypowski, Wojciech
Dębiec, Aleksander
Świstak, Jarosław
Nowocień, Maciej
Rzepecki, Piotr
Możański, Marcin
Staszewski, Jacek
Stępień, Adam
author_sort Szypowski, Wojciech
collection PubMed
description Vaccine-induced immune thrombotic thrombocytopenia (VITT) with cerebral venous sinus thrombosis (CVST) has been recently reported after vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We present a case of a patient with fulminant CVST and thrombocytopenia after receiving the ChAdOx1 nCoV-19 vaccine. Although the patient received immediate anticoagulant and intravenous immune globulin treatment, he died within 24 h after hospital admission. VITT and CVST are rare conditions; however, the course may be fatal. Therefore, clinicians should be familiarized with the clinical and laboratory features of VITT.
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spelling pubmed-88779992022-02-26 Case Report of Cerebral Sinus Thrombosis Related to Immune Thrombotic Thrombocytopenia Following Administration of ChAdOx1 nCoV-19 for Vaccination against COVID-19 Szypowski, Wojciech Dębiec, Aleksander Świstak, Jarosław Nowocień, Maciej Rzepecki, Piotr Możański, Marcin Staszewski, Jacek Stępień, Adam Life (Basel) Case Report Vaccine-induced immune thrombotic thrombocytopenia (VITT) with cerebral venous sinus thrombosis (CVST) has been recently reported after vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We present a case of a patient with fulminant CVST and thrombocytopenia after receiving the ChAdOx1 nCoV-19 vaccine. Although the patient received immediate anticoagulant and intravenous immune globulin treatment, he died within 24 h after hospital admission. VITT and CVST are rare conditions; however, the course may be fatal. Therefore, clinicians should be familiarized with the clinical and laboratory features of VITT. MDPI 2022-01-24 /pmc/articles/PMC8877999/ /pubmed/35207456 http://dx.doi.org/10.3390/life12020168 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Szypowski, Wojciech
Dębiec, Aleksander
Świstak, Jarosław
Nowocień, Maciej
Rzepecki, Piotr
Możański, Marcin
Staszewski, Jacek
Stępień, Adam
Case Report of Cerebral Sinus Thrombosis Related to Immune Thrombotic Thrombocytopenia Following Administration of ChAdOx1 nCoV-19 for Vaccination against COVID-19
title Case Report of Cerebral Sinus Thrombosis Related to Immune Thrombotic Thrombocytopenia Following Administration of ChAdOx1 nCoV-19 for Vaccination against COVID-19
title_full Case Report of Cerebral Sinus Thrombosis Related to Immune Thrombotic Thrombocytopenia Following Administration of ChAdOx1 nCoV-19 for Vaccination against COVID-19
title_fullStr Case Report of Cerebral Sinus Thrombosis Related to Immune Thrombotic Thrombocytopenia Following Administration of ChAdOx1 nCoV-19 for Vaccination against COVID-19
title_full_unstemmed Case Report of Cerebral Sinus Thrombosis Related to Immune Thrombotic Thrombocytopenia Following Administration of ChAdOx1 nCoV-19 for Vaccination against COVID-19
title_short Case Report of Cerebral Sinus Thrombosis Related to Immune Thrombotic Thrombocytopenia Following Administration of ChAdOx1 nCoV-19 for Vaccination against COVID-19
title_sort case report of cerebral sinus thrombosis related to immune thrombotic thrombocytopenia following administration of chadox1 ncov-19 for vaccination against covid-19
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8877999/
https://www.ncbi.nlm.nih.gov/pubmed/35207456
http://dx.doi.org/10.3390/life12020168
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