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β-Catenin-Specific Inhibitor, iCRT14, Promotes BoHV-1 Infection-Induced DNA Damage in Human A549 Lung Adenocarcinoma Cells by Enhancing Viral Protein Expression

Oncolytic bovine herpesvirus type 1 (BoHV-1) infection induces DNA damage in human lung adenocarcinoma cell line A549. However, the underlying mechanisms are not fully understood. We found that BoHV-1 infection decreased the steady-state protein levels of p53-binding protein 1 (53BP1), which plays a...

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Detalles Bibliográficos
Autores principales: Ding, Xiuyan, Yuan, Weifeng, Yang, Hao, Liu, Chang, Li, Shitao, Zhu, Liqian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8878024/
https://www.ncbi.nlm.nih.gov/pubmed/35216447
http://dx.doi.org/10.3390/ijms23042328