Lipophilicity and Pharmacokinetic Properties of New Anticancer Dipyridothiazine with 1,2,3-Triazole Substituents

The lipophilicity parameters (logP(calcd), R(M)(0) and logP(TLC)) of 10 new active anticancer dipirydothiazines with a 1,2,3-triazole ring were determined theoretically using computational methods and experimentally by reversed-phase TLC. Experimental lipophilicity was assessed using mobile phases (...

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Detalles Bibliográficos
Autores principales: Morak-Młodawska, Beata, Jeleń, Małgorzata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8878114/
https://www.ncbi.nlm.nih.gov/pubmed/35209047
http://dx.doi.org/10.3390/molecules27041253

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8878114/
https://www.ncbi.nlm.nih.gov/pubmed/35209047
http://dx.doi.org/10.3390/molecules27041253

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