DogCatcher allows loop-friendly protein-protein ligation

There are many efficient ways to connect proteins at termini. However, connecting at a loop is difficult because of lower flexibility and variable environment. Here, we have developed DogCatcher, a protein that forms a spontaneous isopeptide bond with DogTag peptide. DogTag/DogCatcher was generated...

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Detalles Bibliográficos
Autores principales: Keeble, Anthony H., Yadav, Vikash K., Ferla, Matteo P., Bauer, Claudia C., Chuntharpursat-Bon, Eulashini, Huang, Jin, Bon, Robin S., Howarth, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Resource
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8878318/
https://www.ncbi.nlm.nih.gov/pubmed/34324879
http://dx.doi.org/10.1016/j.chembiol.2021.07.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8878318/
https://www.ncbi.nlm.nih.gov/pubmed/34324879
http://dx.doi.org/10.1016/j.chembiol.2021.07.005

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