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Vitamin D and Calcium Supplementation Accelerate Vascular Calcification in a Model of Pseudoxanthoma Elasticum

Arterial calcification is a common feature of pseudoxanthoma elasticum (PXE), a disease characterized by ABCC6 mutations, inducing a deficiency in pyrophosphate, a key inhibitor of calcium phosphate crystallization in arteries. Methods: we analyzed whether long-term exposure of Abcc6(−/−) mice (a mu...

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Detalles Bibliográficos
Autores principales: Bouderlique, Elise, Tang, Ellie, Zaworski, Jeremy, Coudert, Amélie, Bazin, Dominique, Borondics, Ferenc, Haymann, Jean-Philippe, Leftheriotis, Georges, Martin, Ludovic, Daudon, Michel, Letavernier, Emmanuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8878394/
https://www.ncbi.nlm.nih.gov/pubmed/35216422
http://dx.doi.org/10.3390/ijms23042302