Cargando…

Aging and Clonal Behavior of Hematopoietic Stem Cells

Hematopoietic stem cells (HSCs) are the only cell population that possesses both a self-renewing capacity and multipotency, and can give rise to all lineages of blood cells throughout an organism’s life. However, the self-renewal capacity of HSCs is not infinite, and cumulative evidence suggests tha...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yamashita, Masayuki, Iwama, Atsushi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8878540/ https://www.ncbi.nlm.nih.gov/pubmed/35216063 http://dx.doi.org/10.3390/ijms23041948

Ejemplares similares

Aging and leukemic evolution of hematopoietic stem cells under various stress conditions
por: Kurosawa, Shuhei, et al.
Publicado: (2020)

Limited rejuvenation of aged hematopoietic stem cells in young bone marrow niche
por: Kuribayashi, Wakako, et al.
Publicado: (2020)

Epigenetic Memories in Hematopoietic Stem and Progenitor Cells
por: Aoyama, Kazumasa, et al.
Publicado: (2022)

Clonal Hematopoiesis, Cardiovascular Diseases and Hematopoietic Stem Cells
por: Kandarakov, Oleg, et al.
Publicado: (2020)

Inflammation as a regulator of hematopoietic stem cell function in disease, aging, and clonal selection
por: Caiado, Francisco, et al.
Publicado: (2021)

Clonal analysis reveals multiple functional defects of aged murine hematopoietic stem cells
por: Dykstra, Brad, et al.
Publicado: (2011)

Large-Scale Clonal Analysis Resolves Aging of the Mouse Hematopoietic Stem Cell Compartment
por: Yamamoto, Ryo, et al.
Publicado: (2018)

Quality assurance of hematopoietic stem cells by macrophages determines stem cell clonality
por: Wattrus, Samuel J., et al.
Publicado: (2022)

Epigenetic traits inscribed in chromatin accessibility in aged hematopoietic stem cells
por: Itokawa, Naoki, et al.
Publicado: (2022)

Clonal dominance and transplantation dynamics in hematopoietic stem cell compartments
por: Ashcroft, Peter, et al.
Publicado: (2017)

Innate immune pathways and inflammation in hematopoietic aging, clonal hematopoiesis, and MDS
por: Trowbridge, Jennifer J., et al.
Publicado: (2021)

Acquired Aplastic Anemia as a Clonal Disorder of Hematopoietic Stem Cells
por: Brzeźniakiewicz-Janus, Katarzyna, et al.
Publicado: (2020)

Inflamm-aging of hematopoietic stem cells
por: Chen, Zhiyang, et al.
Publicado: (2019)

Inflammation and hematopoietic stem cells aging
por: He, Hanqing, et al.
Publicado: (2020)

Clonality in haematopoietic stem cell ageing
por: Terradas-Terradas, Maria, et al.
Publicado: (2020)

Quantifying Hematopoietic Stem Cell Clonal Diversity by Selecting Informative Amplicon Barcodes
por: Teets, Emily M., et al.
Publicado: (2020)

Single-cell clonal tracking of persistent T-cells in allogeneic hematopoietic stem cell transplantation
por: Obermayer, Benedikt, et al.
Publicado: (2023)

Causes and Mechanisms of Hematopoietic Stem Cell Aging
por: Lee, Jungwoon, et al.
Publicado: (2019)

Inflammation and Aging of Hematopoietic Stem Cells in Their Niche
por: Yang, Daozheng, et al.
Publicado: (2021)

Mitochondrial Contributions to Hematopoietic Stem Cell Aging
por: Morganti, Claudia, et al.
Publicado: (2021)

Age-related cancer mutations associated with clonal hematopoietic expansion
por: Xie, Mingchao, et al.
Publicado: (2014)

The hematopoietic saga of clonality in sickle cell disease
por: Stonestrom, Aaron J., et al.
Publicado: (2022)

Microenvironmental contributions to hematopoietic stem cell aging
por: Ho, Ya-Hsuan, et al.
Publicado: (2020)

Understanding intrinsic hematopoietic stem cell aging
por: Mejia-Ramirez, Eva, et al.
Publicado: (2020)

Clonal analysis reveals remarkable functional heterogeneity during hematopoietic stem cell emergence
por: Ye, Hui, et al.
Publicado: (2017)

Glucose Metabolism and Aging of Hematopoietic Stem and Progenitor Cells
por: Poisa-Beiro, Laura, et al.
Publicado: (2022)

DNA Damage Response in Hematopoietic Stem Cell Ageing
por: Li, Tangliang, et al.
Publicado: (2016)

Mechanisms and rejuvenation strategies for aged hematopoietic stem cells
por: Li, Xia, et al.
Publicado: (2020)

Hematopoietic Stem Cells and the Immune System in Development and Aging
por: Shevyrev, Daniil, et al.
Publicado: (2023)

Bmi1 Confers Resistance to Oxidative Stress on Hematopoietic Stem Cells
por: Nakamura, Shunsuke, et al.
Publicado: (2012)

Ex Vivo Expansion of Human Hematopoietic Stem Cells by Garcinol, a Potent Inhibitor of Histone Acetyltransferase
por: Nishino, Taito, et al.
Publicado: (2011)

Non-conditioned bone marrow chimeric mouse generation using culture-based enrichment of hematopoietic stem and progenitor cells
por: Ochi, Kiyosumi, et al.
Publicado: (2021)

Efficient gene editing of human long-term hematopoietic stem cells validated by clonal tracking
por: Ferrari, Samuele, et al.
Publicado: (2020)

Molecular and cellular mechanisms of aging in hematopoietic stem cells and their niches
por: Zhang, Lei, et al.
Publicado: (2020)

Non-Lethal Ionizing Radiation Promotes Aging-Like Phenotypic Changes of Human Hematopoietic Stem and Progenitor Cells in Humanized Mice
por: Wang, Changshan, et al.
Publicado: (2015)

Growing and aging of hematopoietic stem cells
por: Udroiu, Ion, et al.
Publicado: (2021)

The Role of Nutrients in Maintaining Hematopoietic Stem Cells and Healthy Hematopoiesis for Life
por: Tadokoro, Yuko, et al.
Publicado: (2022)

In Vivo Clonal Analysis Reveals Random Monoallelic Expression in Lymphocytes That Traces Back to Hematopoietic Stem Cells
por: Kubasova, Nadiya, et al.
Publicado: (2022)

Clonal expansion capacity defines two consecutive developmental stages of long-term hematopoietic stem cells
por: Grinenko, Tatyana, et al.
Publicado: (2014)

Multiomics of three hematological malignancies in a patient reveal their origin from clonal hematopoietic stem cells
por: Mayeur, Sylvain, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_lqdpmg22fk3jc5onhbl2fpha41