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Validation of a Rapid and Easy-to-Apply Method to Simultaneously Quantify Co-Loaded Dexamethasone and Melatonin PLGA Microspheres by HPLC-UV: Encapsulation Efficiency and In Vitro Release

This paper discusses the development and validation of a rapid method for the reversed phase HPLC-UV quantification of biodegradable poly(D,L-lactic-co-glycolic) acid (PLGA) microspheres co-loaded with two neuroprotective agents (dexamethasone and melatonin) (DX-MEL-MSs) to be intravitreally adminis...

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Detalles Bibliográficos
Autores principales:	Brugnera, Marco, Vicario-de-la-Torre, Marta, Andrés-Guerrero, Vanessa, Bravo-Osuna, Irene, Molina-Martínez, Irene Teresa, Herrero-Vanrell, Rocío
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8878730/ https://www.ncbi.nlm.nih.gov/pubmed/35214021 http://dx.doi.org/10.3390/pharmaceutics14020288

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