Cargando…
A Novel Mutation in a Gene Causes Sclerosteosis in a Family of Mediterranean Origin
Background and Objectives: Sclerostin is an SOST gene product that inhibits osteoblast activity and prevents excessive bone formation by antagonizing the Wnt signaling pathway. Sclerosteosis has been linked to loss of function mutations in the SOST gene. It is a rare autosomal recessive disorder cha...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8878747/ https://www.ncbi.nlm.nih.gov/pubmed/35208525 http://dx.doi.org/10.3390/medicina58020202 |