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Targeted Suppression of Lipoprotein Receptor LSR in Astrocytes Leads to Olfactory and Memory Deficits in Mice

Perturbations of cholesterol metabolism have been linked to neurodegenerative diseases. Glia–neuron crosstalk is essential to achieve a tight regulation of brain cholesterol trafficking. Adequate cholesterol supply from glia via apolipoprotein E-containing lipoproteins ensures neuronal development a...

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Detalles Bibliográficos
Autores principales: El Hajj, Aseel, Herzine, Ameziane, Calcagno, Gaetano, Désor, Frédéric, Djelti, Fathia, Bombail, Vincent, Denis, Isabelle, Oster, Thierry, Malaplate, Catherine, Vigier, Maxime, Kaminski, Sandra, Pauron, Lynn, Corbier, Catherine, Yen, Frances T., Lanhers, Marie-Claire, Claudepierre, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8878779/
https://www.ncbi.nlm.nih.gov/pubmed/35216163
http://dx.doi.org/10.3390/ijms23042049

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