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Superiority of Mesoporous Silica-Based Amorphous Formulations over Spray-Dried Solid Dispersions

The aim of this study was to compare the performance of two amorphous formulation strategies: mesoporous silica via solvent impregnation, and solid dispersions by spray drying. Poorly soluble fenofibrate was chosen as the model drug compound. A total of 30% Fenofibrate-loaded mesoporous silica and s...

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Detalles Bibliográficos
Autores principales:	Zhang, Hongwei, Li, Minglu, Li, Jianmin, Agrawal, Anjali, Hui, Ho-Wah, Liu, Demin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8878785/ https://www.ncbi.nlm.nih.gov/pubmed/35214159 http://dx.doi.org/10.3390/pharmaceutics14020428

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