Cargando…

Chest Imaging for Pulmonary TB—An Update

The diagnosis of pulmonary tuberculosis (PTB) in children is challenging. Difficulties in acquiring suitable specimens, pauci-bacillary load, and limitations of current diagnostic methods often make microbiological confirmation difficult. Chest imaging provides an additional diagnostic modality that...

Descripción completa

Detalles Bibliográficos
Autores principales: Nel, Michael, Franckling-Smith, Zoe, Pillay, Tanyia, Andronikou, Savvas, Zar, Heather J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8878790/
https://www.ncbi.nlm.nih.gov/pubmed/35215104
http://dx.doi.org/10.3390/pathogens11020161
_version_ 1784658744055955456
author Nel, Michael
Franckling-Smith, Zoe
Pillay, Tanyia
Andronikou, Savvas
Zar, Heather J.
author_facet Nel, Michael
Franckling-Smith, Zoe
Pillay, Tanyia
Andronikou, Savvas
Zar, Heather J.
author_sort Nel, Michael
collection PubMed
description The diagnosis of pulmonary tuberculosis (PTB) in children is challenging. Difficulties in acquiring suitable specimens, pauci-bacillary load, and limitations of current diagnostic methods often make microbiological confirmation difficult. Chest imaging provides an additional diagnostic modality that is frequently used in clinical practice. Chest imaging can also provide insight into treatment response and identify development of disease complications. Despite widespread use, chest radiographs are usually non-specific and have high inter- and intra-observer variability. Other diagnostic imaging modalities such as ultrasound, computed tomography (CT), and magnetic resonance imaging (MRI) can provide additional information to substantiate diagnosis. In this review, we discuss the radiological features of PTB in each modality, highlighting the advantages and limitations of each. We also address newer imaging technologies and potential use.
format Online
Article
Text
id pubmed-8878790
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-88787902022-02-26 Chest Imaging for Pulmonary TB—An Update Nel, Michael Franckling-Smith, Zoe Pillay, Tanyia Andronikou, Savvas Zar, Heather J. Pathogens Review The diagnosis of pulmonary tuberculosis (PTB) in children is challenging. Difficulties in acquiring suitable specimens, pauci-bacillary load, and limitations of current diagnostic methods often make microbiological confirmation difficult. Chest imaging provides an additional diagnostic modality that is frequently used in clinical practice. Chest imaging can also provide insight into treatment response and identify development of disease complications. Despite widespread use, chest radiographs are usually non-specific and have high inter- and intra-observer variability. Other diagnostic imaging modalities such as ultrasound, computed tomography (CT), and magnetic resonance imaging (MRI) can provide additional information to substantiate diagnosis. In this review, we discuss the radiological features of PTB in each modality, highlighting the advantages and limitations of each. We also address newer imaging technologies and potential use. MDPI 2022-01-26 /pmc/articles/PMC8878790/ /pubmed/35215104 http://dx.doi.org/10.3390/pathogens11020161 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Nel, Michael
Franckling-Smith, Zoe
Pillay, Tanyia
Andronikou, Savvas
Zar, Heather J.
Chest Imaging for Pulmonary TB—An Update
title Chest Imaging for Pulmonary TB—An Update
title_full Chest Imaging for Pulmonary TB—An Update
title_fullStr Chest Imaging for Pulmonary TB—An Update
title_full_unstemmed Chest Imaging for Pulmonary TB—An Update
title_short Chest Imaging for Pulmonary TB—An Update
title_sort chest imaging for pulmonary tb—an update
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8878790/
https://www.ncbi.nlm.nih.gov/pubmed/35215104
http://dx.doi.org/10.3390/pathogens11020161
work_keys_str_mv AT nelmichael chestimagingforpulmonarytbanupdate
AT francklingsmithzoe chestimagingforpulmonarytbanupdate
AT pillaytanyia chestimagingforpulmonarytbanupdate
AT andronikousavvas chestimagingforpulmonarytbanupdate
AT zarheatherj chestimagingforpulmonarytbanupdate