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Chest Imaging for Pulmonary TB—An Update
The diagnosis of pulmonary tuberculosis (PTB) in children is challenging. Difficulties in acquiring suitable specimens, pauci-bacillary load, and limitations of current diagnostic methods often make microbiological confirmation difficult. Chest imaging provides an additional diagnostic modality that...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8878790/ https://www.ncbi.nlm.nih.gov/pubmed/35215104 http://dx.doi.org/10.3390/pathogens11020161 |
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author | Nel, Michael Franckling-Smith, Zoe Pillay, Tanyia Andronikou, Savvas Zar, Heather J. |
author_facet | Nel, Michael Franckling-Smith, Zoe Pillay, Tanyia Andronikou, Savvas Zar, Heather J. |
author_sort | Nel, Michael |
collection | PubMed |
description | The diagnosis of pulmonary tuberculosis (PTB) in children is challenging. Difficulties in acquiring suitable specimens, pauci-bacillary load, and limitations of current diagnostic methods often make microbiological confirmation difficult. Chest imaging provides an additional diagnostic modality that is frequently used in clinical practice. Chest imaging can also provide insight into treatment response and identify development of disease complications. Despite widespread use, chest radiographs are usually non-specific and have high inter- and intra-observer variability. Other diagnostic imaging modalities such as ultrasound, computed tomography (CT), and magnetic resonance imaging (MRI) can provide additional information to substantiate diagnosis. In this review, we discuss the radiological features of PTB in each modality, highlighting the advantages and limitations of each. We also address newer imaging technologies and potential use. |
format | Online Article Text |
id | pubmed-8878790 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-88787902022-02-26 Chest Imaging for Pulmonary TB—An Update Nel, Michael Franckling-Smith, Zoe Pillay, Tanyia Andronikou, Savvas Zar, Heather J. Pathogens Review The diagnosis of pulmonary tuberculosis (PTB) in children is challenging. Difficulties in acquiring suitable specimens, pauci-bacillary load, and limitations of current diagnostic methods often make microbiological confirmation difficult. Chest imaging provides an additional diagnostic modality that is frequently used in clinical practice. Chest imaging can also provide insight into treatment response and identify development of disease complications. Despite widespread use, chest radiographs are usually non-specific and have high inter- and intra-observer variability. Other diagnostic imaging modalities such as ultrasound, computed tomography (CT), and magnetic resonance imaging (MRI) can provide additional information to substantiate diagnosis. In this review, we discuss the radiological features of PTB in each modality, highlighting the advantages and limitations of each. We also address newer imaging technologies and potential use. MDPI 2022-01-26 /pmc/articles/PMC8878790/ /pubmed/35215104 http://dx.doi.org/10.3390/pathogens11020161 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Nel, Michael Franckling-Smith, Zoe Pillay, Tanyia Andronikou, Savvas Zar, Heather J. Chest Imaging for Pulmonary TB—An Update |
title | Chest Imaging for Pulmonary TB—An Update |
title_full | Chest Imaging for Pulmonary TB—An Update |
title_fullStr | Chest Imaging for Pulmonary TB—An Update |
title_full_unstemmed | Chest Imaging for Pulmonary TB—An Update |
title_short | Chest Imaging for Pulmonary TB—An Update |
title_sort | chest imaging for pulmonary tb—an update |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8878790/ https://www.ncbi.nlm.nih.gov/pubmed/35215104 http://dx.doi.org/10.3390/pathogens11020161 |
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