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Monte Carlo Characterization of the Trimage Brain PET System

The TRIMAGE project aims to develop a brain-dedicated PET/MR/EEG (Positron Emission Tomography/Magnetic Resonance/Electroencephalogram) system that is able to perform simultaneous PET, MR and EEG acquisitions. The PET component consists of a full ring with 18 sectors. Each sector includes three squa...

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Autores principales: Masturzo, Luigi, Carra, Pietro, Erba, Paola Anna, Morrocchi, Matteo, Pilleri, Alessandro, Sportelli, Giancarlo, Belcari, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8878795/
https://www.ncbi.nlm.nih.gov/pubmed/35200724
http://dx.doi.org/10.3390/jimaging8020021
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author Masturzo, Luigi
Carra, Pietro
Erba, Paola Anna
Morrocchi, Matteo
Pilleri, Alessandro
Sportelli, Giancarlo
Belcari, Nicola
author_facet Masturzo, Luigi
Carra, Pietro
Erba, Paola Anna
Morrocchi, Matteo
Pilleri, Alessandro
Sportelli, Giancarlo
Belcari, Nicola
author_sort Masturzo, Luigi
collection PubMed
description The TRIMAGE project aims to develop a brain-dedicated PET/MR/EEG (Positron Emission Tomography/Magnetic Resonance/Electroencephalogram) system that is able to perform simultaneous PET, MR and EEG acquisitions. The PET component consists of a full ring with 18 sectors. Each sector includes three square detector modules based on dual sstaggered LYSO:Ce matrices read out by SiPMs. Using Monte Carlo simulations and following NEMA (National Electrical Manufacturers Association) guidelines, image quality procedures have been applied to evaluate the performance of the PET component of the system. The performance are reported in terms of spatial resolution, uniformity, recovery coefficient, spill over ratio, noise equivalent count rate (NECR) and scatter fraction. The results show that the TRIMAGE system is at the top of the current brain PET technologies.
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spelling pubmed-88787952022-02-26 Monte Carlo Characterization of the Trimage Brain PET System Masturzo, Luigi Carra, Pietro Erba, Paola Anna Morrocchi, Matteo Pilleri, Alessandro Sportelli, Giancarlo Belcari, Nicola J Imaging Article The TRIMAGE project aims to develop a brain-dedicated PET/MR/EEG (Positron Emission Tomography/Magnetic Resonance/Electroencephalogram) system that is able to perform simultaneous PET, MR and EEG acquisitions. The PET component consists of a full ring with 18 sectors. Each sector includes three square detector modules based on dual sstaggered LYSO:Ce matrices read out by SiPMs. Using Monte Carlo simulations and following NEMA (National Electrical Manufacturers Association) guidelines, image quality procedures have been applied to evaluate the performance of the PET component of the system. The performance are reported in terms of spatial resolution, uniformity, recovery coefficient, spill over ratio, noise equivalent count rate (NECR) and scatter fraction. The results show that the TRIMAGE system is at the top of the current brain PET technologies. MDPI 2022-01-23 /pmc/articles/PMC8878795/ /pubmed/35200724 http://dx.doi.org/10.3390/jimaging8020021 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Masturzo, Luigi
Carra, Pietro
Erba, Paola Anna
Morrocchi, Matteo
Pilleri, Alessandro
Sportelli, Giancarlo
Belcari, Nicola
Monte Carlo Characterization of the Trimage Brain PET System
title Monte Carlo Characterization of the Trimage Brain PET System
title_full Monte Carlo Characterization of the Trimage Brain PET System
title_fullStr Monte Carlo Characterization of the Trimage Brain PET System
title_full_unstemmed Monte Carlo Characterization of the Trimage Brain PET System
title_short Monte Carlo Characterization of the Trimage Brain PET System
title_sort monte carlo characterization of the trimage brain pet system
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8878795/
https://www.ncbi.nlm.nih.gov/pubmed/35200724
http://dx.doi.org/10.3390/jimaging8020021
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