A Novel Small Molecular Prostaglandin Receptor EP4 Antagonist, L001, Suppresses Pancreatic Cancer Metastasis

Metastatic pancreatic cancer remains a major clinical challenge, emphasizing the urgent need for the exploitation of novel therapeutic approaches with superior response. In this study, we demonstrate that the aberrant activation of prostaglandin E(2) (PGE(2)) receptor 4 (EP4) is a pro-metastatic sig...

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Detalles Bibliográficos
Autores principales: He, Jiacheng, Lin, Xianhua, Meng, Fanhui, Zhao, Yumiao, Wang, Wei, Zhang, Yao, Chai, Xiaolei, Zhang, Ying, Yu, Weiwei, Yang, Junjie, Li, Guichao, Du, Xuekui, Zhang, Hankun, Liu, Mingyao, Lu, Weiqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8879074/
https://www.ncbi.nlm.nih.gov/pubmed/35208999
http://dx.doi.org/10.3390/molecules27041209

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