HIV-1 Nucleocapsid Protein Binds Double-Stranded DNA in Multiple Modes to Regulate Compaction and Capsid Uncoating

The HIV-1 nucleocapsid protein (NC) is a multi-functional protein necessary for viral replication. Recent studies have demonstrated reverse transcription occurs inside the fully intact viral capsid and that the timing of reverse transcription and uncoating are correlated. How a nearly 10 kbp viral D...

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Detalles Bibliográficos
Autores principales: Gien, Helena, Morse, Michael, McCauley, Micah J., Kitzrow, Jonathan P., Musier-Forsyth, Karin, Gorelick, Robert J., Rouzina, Ioulia, Williams, Mark C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8879225/
https://www.ncbi.nlm.nih.gov/pubmed/35215829
http://dx.doi.org/10.3390/v14020235

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8879225/
https://www.ncbi.nlm.nih.gov/pubmed/35215829
http://dx.doi.org/10.3390/v14020235

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