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Unnatural Biosynthesis by an Engineered Microorganism with Heterologously Expressed Natural Enzymes and an Artificial Metalloenzyme
Synthetic biology enables microbial hosts to produce complex molecules that are otherwise produced by organisms that are rare or difficult to cultivate, but the structures of these molecules are limited to those formed by chemical reactions catalyzed by natural enzymes. The integration of artificial...
Autores principales: | Huang, Jing, Liu, Zhennan, Bloomer, Brandon, Clark, Douglas, Mukhopadhyay, Aindrila, Keasling, Jay, Hartwig, John |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8879416/ https://www.ncbi.nlm.nih.gov/pubmed/34650235 http://dx.doi.org/10.1038/s41557-021-00801-3 |
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