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Phytochemical Characterizations of Maranthes polyandra (Benth.) Prance

Two new ursane-type triterpenoids, named Polyanside A (1) and B (2), along with eleven known compounds (3–13), were isolated and elucidated from Maranthes polyandra (Benth.) Prance. The structures of these compounds were elucidated based on chemical evidence and multiple spectroscopic data. Isolated...

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Detalles Bibliográficos
Autores principales: Ali, Nida, Khan, Farooq-Ahmad, Salawu, Kayode Muritala, Irshad, Rimsha, Jabeen, Almas, Zhang, Chun-Lei, Choudhary, Muhammad Iqbal, Liu, Xin-Min, Wang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8879441/
https://www.ncbi.nlm.nih.gov/pubmed/35209101
http://dx.doi.org/10.3390/molecules27041316
Descripción
Sumario:Two new ursane-type triterpenoids, named Polyanside A (1) and B (2), along with eleven known compounds (3–13), were isolated and elucidated from Maranthes polyandra (Benth.) Prance. The structures of these compounds were elucidated based on chemical evidence and multiple spectroscopic data. Isolated compounds were evaluated for anti-cancer, anti-inflammatory activities, and cytotoxicity on a normal human cell line (BJ). None of them showed activity and cytotoxicity. The hexane fraction was analyzed by GC-MS, resulting in the identification of forty-one compounds. This is the first comprehensive study on the phytochemistry of M. polyandra.