“Superwobbling” and tRNA-34 Wobble and tRNA-37 Anticodon Loop Modifications in Evolution and Devolution of the Genetic Code

The genetic code evolved around the reading of the tRNA anticodon on the primitive ribosome, and tRNA-34 wobble and tRNA-37 modifications coevolved with the code. We posit that EF-Tu, the closing mechanism of the 30S ribosomal subunit, methylation of wobble U34 at the 5-carbon and suppression of wob...

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Detalles Bibliográficos
Autores principales: Lei, Lei, Burton, Zachary Frome
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8879553/
https://www.ncbi.nlm.nih.gov/pubmed/35207539
http://dx.doi.org/10.3390/life12020252

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8879553/
https://www.ncbi.nlm.nih.gov/pubmed/35207539
http://dx.doi.org/10.3390/life12020252

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