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Prevalence of Borrelia burgdorferi in Ixodidae Tick around Asia: A Systematic Review and Meta-Analysis

Lyme disease (LD) is a common arthropod-borne inflammatory disorder prevalent in the northern hemisphere. LD is caused by a spirochete named Borrelia burgdorferi s.l., which is transmitted to humans by ticks. Climate, environment, and other factors affect land use; recreational-behavior changes affe...

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Autores principales: Ji, Zhenhua, Jian, Miaomiao, Yue, Peng, Cao, Wenjing, Xu, Xin, Zhang, Yu, Pan, Yingyi, Yang, Jiaru, Chen, Jingjing, Liu, Meixiao, Fan, Yuxin, Su, Xuan, Wen, Shiyuan, Kong, Jing, Li, Bingxue, Dong, Yan, Zhou, Guozhong, Liu, Aihua, Bao, Fukai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8879681/
https://www.ncbi.nlm.nih.gov/pubmed/35215089
http://dx.doi.org/10.3390/pathogens11020143
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author Ji, Zhenhua
Jian, Miaomiao
Yue, Peng
Cao, Wenjing
Xu, Xin
Zhang, Yu
Pan, Yingyi
Yang, Jiaru
Chen, Jingjing
Liu, Meixiao
Fan, Yuxin
Su, Xuan
Wen, Shiyuan
Kong, Jing
Li, Bingxue
Dong, Yan
Zhou, Guozhong
Liu, Aihua
Bao, Fukai
author_facet Ji, Zhenhua
Jian, Miaomiao
Yue, Peng
Cao, Wenjing
Xu, Xin
Zhang, Yu
Pan, Yingyi
Yang, Jiaru
Chen, Jingjing
Liu, Meixiao
Fan, Yuxin
Su, Xuan
Wen, Shiyuan
Kong, Jing
Li, Bingxue
Dong, Yan
Zhou, Guozhong
Liu, Aihua
Bao, Fukai
author_sort Ji, Zhenhua
collection PubMed
description Lyme disease (LD) is a common arthropod-borne inflammatory disorder prevalent in the northern hemisphere. LD is caused by a spirochete named Borrelia burgdorferi s.l., which is transmitted to humans by ticks. Climate, environment, and other factors affect land use; recreational-behavior changes affect human contact with infected ticks. Studies in Europe and North America have looked at these aspects, but studies in Asia have not. We searched databases to identify all relevant abstracts published until March 2021. A meta-analysis was undertaken using the standard methods and procedures established by the Cochrane Collaboration. Ninety-one articles were included in our meta-analysis. The literature search identified data from nine countries (China, Japan, Malaysia, Mongolia, Pakistan, Russia Siberia region, South Korea, Thailand and Turkey). Furthermore, 53,003 ticks from six genera (Amblyomma, Dermacentor, Haemaphysalis, Hyalomma, Ixodes and Rhipicephalus) were inspected for infection with B. burgdorferi. The pooled prevalence was 11.1% (95% CI = 8.3–14.2%). Among the nine countries, China had the most studies (56) and Malaysia had the highest infection rate (46.2%). Most infected ticks were from the genera Ixodes and Haemaphysalis. Ticks of the genus Ixodes had the highest infection rate (16.9%). Obvious heterogeneity was noted in our meta-analysis. We analyzed the heterogeneity with regard to countries, genera, time points, and detection methods. This study suggests that Ixodes, Haemaphysalis and Dermacentor may be the most common tike of B. burgdorferi-positive in Asia. The highest proportion of ticks infected by B. burgdorferi were from the genus Ixodes. This meta-analysis is the first attempt to explain the B. burgdorferi infection of hard-body ticks in Asia. The infection rate for each country and infection rate of different tick genera were analyzed: there were large differences between them. The literature is concentrates mainly on East Asia, and data are limited. Our study can provide a reference for a more comprehensive and in-depth investigation of ticks in Asia infected by B. burgdorferi spirochetes.
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spelling pubmed-88796812022-02-26 Prevalence of Borrelia burgdorferi in Ixodidae Tick around Asia: A Systematic Review and Meta-Analysis Ji, Zhenhua Jian, Miaomiao Yue, Peng Cao, Wenjing Xu, Xin Zhang, Yu Pan, Yingyi Yang, Jiaru Chen, Jingjing Liu, Meixiao Fan, Yuxin Su, Xuan Wen, Shiyuan Kong, Jing Li, Bingxue Dong, Yan Zhou, Guozhong Liu, Aihua Bao, Fukai Pathogens Review Lyme disease (LD) is a common arthropod-borne inflammatory disorder prevalent in the northern hemisphere. LD is caused by a spirochete named Borrelia burgdorferi s.l., which is transmitted to humans by ticks. Climate, environment, and other factors affect land use; recreational-behavior changes affect human contact with infected ticks. Studies in Europe and North America have looked at these aspects, but studies in Asia have not. We searched databases to identify all relevant abstracts published until March 2021. A meta-analysis was undertaken using the standard methods and procedures established by the Cochrane Collaboration. Ninety-one articles were included in our meta-analysis. The literature search identified data from nine countries (China, Japan, Malaysia, Mongolia, Pakistan, Russia Siberia region, South Korea, Thailand and Turkey). Furthermore, 53,003 ticks from six genera (Amblyomma, Dermacentor, Haemaphysalis, Hyalomma, Ixodes and Rhipicephalus) were inspected for infection with B. burgdorferi. The pooled prevalence was 11.1% (95% CI = 8.3–14.2%). Among the nine countries, China had the most studies (56) and Malaysia had the highest infection rate (46.2%). Most infected ticks were from the genera Ixodes and Haemaphysalis. Ticks of the genus Ixodes had the highest infection rate (16.9%). Obvious heterogeneity was noted in our meta-analysis. We analyzed the heterogeneity with regard to countries, genera, time points, and detection methods. This study suggests that Ixodes, Haemaphysalis and Dermacentor may be the most common tike of B. burgdorferi-positive in Asia. The highest proportion of ticks infected by B. burgdorferi were from the genus Ixodes. This meta-analysis is the first attempt to explain the B. burgdorferi infection of hard-body ticks in Asia. The infection rate for each country and infection rate of different tick genera were analyzed: there were large differences between them. The literature is concentrates mainly on East Asia, and data are limited. Our study can provide a reference for a more comprehensive and in-depth investigation of ticks in Asia infected by B. burgdorferi spirochetes. MDPI 2022-01-24 /pmc/articles/PMC8879681/ /pubmed/35215089 http://dx.doi.org/10.3390/pathogens11020143 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Ji, Zhenhua
Jian, Miaomiao
Yue, Peng
Cao, Wenjing
Xu, Xin
Zhang, Yu
Pan, Yingyi
Yang, Jiaru
Chen, Jingjing
Liu, Meixiao
Fan, Yuxin
Su, Xuan
Wen, Shiyuan
Kong, Jing
Li, Bingxue
Dong, Yan
Zhou, Guozhong
Liu, Aihua
Bao, Fukai
Prevalence of Borrelia burgdorferi in Ixodidae Tick around Asia: A Systematic Review and Meta-Analysis
title Prevalence of Borrelia burgdorferi in Ixodidae Tick around Asia: A Systematic Review and Meta-Analysis
title_full Prevalence of Borrelia burgdorferi in Ixodidae Tick around Asia: A Systematic Review and Meta-Analysis
title_fullStr Prevalence of Borrelia burgdorferi in Ixodidae Tick around Asia: A Systematic Review and Meta-Analysis
title_full_unstemmed Prevalence of Borrelia burgdorferi in Ixodidae Tick around Asia: A Systematic Review and Meta-Analysis
title_short Prevalence of Borrelia burgdorferi in Ixodidae Tick around Asia: A Systematic Review and Meta-Analysis
title_sort prevalence of borrelia burgdorferi in ixodidae tick around asia: a systematic review and meta-analysis
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8879681/
https://www.ncbi.nlm.nih.gov/pubmed/35215089
http://dx.doi.org/10.3390/pathogens11020143
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